Amino acid sensing using aminoacyl-tRNA synthetase

Akimitsu Kugimiya, Miki Morii, Takashi Ohtsuki

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The detection of amino acids using aminoacyl-tRNA synthetases (ARSs) as the molecular recognition element was proposed, and the binding activity and specificity of ARSs were evaluated. Using this rapid and easy method, from 15 to 50 μM tyrosine could be measured specifically. The method suggested in this article could be realized without an amino acid labeling process or a large volume of organic solvents, and the time for measurement was reasonable.

Original languageEnglish
Pages (from-to)90-92
Number of pages3
JournalAnalytical Biochemistry
Volume378
Issue number1
DOIs
Publication statusPublished - Jul 1 2008

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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