Abstract
The double alkylation of bis[2-(2-lithio-1,3-dithian)-yl]diorganosilane with bis(bromomethyl)diorganosilanes proceeds smoothly in good yields in a mixture of THF-hexamethylphosphoric trianide (HMPA) or THF-1,1,3,3- tetramethylurea (TMU) to give 1,4-disilacyclohexanes whose conformation was shown to be a twist-boat on the basis of X-ray analysis.
| Original language | English |
|---|---|
| Pages (from-to) | 3197-3200 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 39 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - May 14 1998 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Cite this
Shimizu, M., Iwakubo, M., Nishihara, Y., & Hiyama, T. (1998). Alkylation methodology for the synthesis of 1,4-disilacyclohexanes using α,α'-dilithiated silanes. Tetrahedron Letters, 39(20), 3197-3200. https://doi.org/10.1016/S0040-4039(98)00458-4