Aldehyde-selective addition of alkynylchromium compounds prepared by reduction of alkynyl halides with chromium(II) reagent

Kazuhiko Takai, Tooru Kuroda, Shigeki Nakatsukasa, Koichiro Oshima, Hitosi Nozakil

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Alkynyl halides are reduced by chromium(II) chloride in DMF to give unisolable alkynylchromium compounds which add selectively to an aldehyde moiety without affecting the coexisting ketone group of the substrate.

Original languageEnglish
Pages (from-to)5585-5588
Number of pages4
JournalTetrahedron Letters
Volume26
Issue number45
DOIs
Publication statusPublished - 1985
Externally publishedYes

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Chromium
Ketones
Aldehydes
Chlorides
Substrates
chromous chloride

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Aldehyde-selective addition of alkynylchromium compounds prepared by reduction of alkynyl halides with chromium(II) reagent. / Takai, Kazuhiko; Kuroda, Tooru; Nakatsukasa, Shigeki; Oshima, Koichiro; Nozakil, Hitosi.

In: Tetrahedron Letters, Vol. 26, No. 45, 1985, p. 5585-5588.

Research output: Contribution to journalArticle

Takai, Kazuhiko ; Kuroda, Tooru ; Nakatsukasa, Shigeki ; Oshima, Koichiro ; Nozakil, Hitosi. / Aldehyde-selective addition of alkynylchromium compounds prepared by reduction of alkynyl halides with chromium(II) reagent. In: Tetrahedron Letters. 1985 ; Vol. 26, No. 45. pp. 5585-5588.
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