Age-related changes ofurinary nitrite/nitrate excretion in normal children

Hirokazu Tsukahara; Masahiro Hiraoka; Chikahide Hori; Takeshi Miyanomae; Kiyoshi Kikuchi; Masakatsu Sudo

doi:10.1159/000190196

Age-related changes ofurinary nitrite/nitrate excretion in normal children

Hirokazu Tsukahara, Masahiro Hiraoka, Chikahide Hori, Takeshi Miyanomae, Kiyoshi Kikuchi, Masakatsu Sudo

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We measured the urinary excretion of nitrite/nitrate, stable metabolites of nitric oxide, using the brucine method in 90 healthy normal children (47 boys and 43 girls), aged from 1.0 to 17.1 years, to establish the age-related normal range in children. The urinary nitrite/nitrate excretion was highest in the youngest children and decreased in an age-dependent manner to reach constant levels at about 12 years of agein both sexes. The data may be useful in identifying sick children with abnormal nitric oxide production.

Original language	English
Pages (from-to)	307-309
Number of pages	3
Journal	Nephron
Volume	76
Issue number	3
DOIs	https://doi.org/10.1159/000190196
Publication status	Published - 1997
Externally published	Yes

Keywords

Age
Nitric oxide
Normal children
Urinary nitrite/nitrate

ASJC Scopus subject areas

Physiology
Nephrology
Physiology (medical)
Urology

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10.1159/000190196

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abstract = "We measured the urinary excretion of nitrite/nitrate, stable metabolites of nitric oxide, using the brucine method in 90 healthy normal children (47 boys and 43 girls), aged from 1.0 to 17.1 years, to establish the age-related normal range in children. The urinary nitrite/nitrate excretion was highest in the youngest children and decreased in an age-dependent manner to reach constant levels at about 12 years of agein both sexes. The data may be useful in identifying sick children with abnormal nitric oxide production.",

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AU - Tsukahara, Hirokazu

AU - Hiraoka, Masahiro

AU - Hori, Chikahide

AU - Miyanomae, Takeshi

AU - Kikuchi, Kiyoshi

AU - Sudo, Masakatsu

PY - 1997

Y1 - 1997

N2 - We measured the urinary excretion of nitrite/nitrate, stable metabolites of nitric oxide, using the brucine method in 90 healthy normal children (47 boys and 43 girls), aged from 1.0 to 17.1 years, to establish the age-related normal range in children. The urinary nitrite/nitrate excretion was highest in the youngest children and decreased in an age-dependent manner to reach constant levels at about 12 years of agein both sexes. The data may be useful in identifying sick children with abnormal nitric oxide production.

AB - We measured the urinary excretion of nitrite/nitrate, stable metabolites of nitric oxide, using the brucine method in 90 healthy normal children (47 boys and 43 girls), aged from 1.0 to 17.1 years, to establish the age-related normal range in children. The urinary nitrite/nitrate excretion was highest in the youngest children and decreased in an age-dependent manner to reach constant levels at about 12 years of agein both sexes. The data may be useful in identifying sick children with abnormal nitric oxide production.

KW - Age

KW - Nitric oxide

KW - Normal children

KW - Urinary nitrite/nitrate

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Age-related changes ofurinary nitrite/nitrate excretion in normal children

Abstract

Keywords

ASJC Scopus subject areas

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