Age-related changes of IgE-mediated allergic reaction in patients with late onset asthma - Relationship between IgE-mediated allergy and age at onset

S. Yokota, Fumihiro Mitsunobu, T. Mifune, Y. Hosaki, Kozo Ashida, H. Tsugeno, Y. Tanizaki

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We examined age-related changes in the IgE-mediated allergic reaction in patients with late-onset asthma, whose asthma first occurred at over 40 years. (1)The number of patients with a high serum IgE level (over 300IU/ml) was larger in patients with an age of onset between 40 and 49 (40~49 years group) and in patients older than 60 at age of onset (60~year group) than in patients with an age of onset between 50 and 59 (50~59 year group). (2)A positive RAST score to house dust mite (HDm) allergen was more frequently found in the 40~49 year group and in the 60~ year group than in the 50 ~59 year group. Frequency of positive RAST score to HDm in the 50~59 year group was significantly lower (p

Original languageEnglish
Pages (from-to)367-373
Number of pages7
JournalJapanese Journal of Geriatrics
Volume35
Issue number5
Publication statusPublished - 1998

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Age of Onset
Immunoglobulin E
Hypersensitivity
Asthma
Dermatophagoides Antigens
Pyroglyphidae
Serum

Keywords

  • Aging at asthma onset
  • Family history of atopy
  • Inhalant allergen of RAST
  • Late onset asthma
  • Serum IgE level

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Age-related changes of IgE-mediated allergic reaction in patients with late onset asthma - Relationship between IgE-mediated allergy and age at onset. / Yokota, S.; Mitsunobu, Fumihiro; Mifune, T.; Hosaki, Y.; Ashida, Kozo; Tsugeno, H.; Tanizaki, Y.

In: Japanese Journal of Geriatrics, Vol. 35, No. 5, 1998, p. 367-373.

Research output: Contribution to journalArticle

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AU - Tsugeno, H.

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