Age-Dependent Spike Localization in Various Epileptic Syndromes

Harumi Yoshinaga, Katsuhiro Kobayashi, Yumiko Ishizaki, Mari Wakai, Yusuke Tominaga, Takanori Matsuoka, Yoko Ohtsuka

Research output: Contribution to journalArticle

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Abstract

The electroencephalograms from 276 patients with localization-related epilepsy were analyzed to compare the distribution of spike foci in different age groups. Patients were divided into five groups according to spike location in the frontal, central, temporal, occipital, or multiple cortical regions. The age of peak incidence was earliest in patients with occipital foci, followed by those with central foci and then those with frontal foci. A bimodal age distribution of patients with temporal foci was observed. Symptomatic patients frequently exhibited multiple and frontal foci, and a large number of idiopathic patients had central, temporal, and occipital foci. Multiple foci were detected in 27.5% of idiopathic patients. Age-related spike localization was uniformly observed, regardless of the epileptic syndrome. The analysis of these data indicates that there are two types of multiple foci, one correlated with organic lesions and the other with an idiopathic, functional nature.

Original languageEnglish
Pages (from-to)440-444
Number of pages5
JournalPediatric Neurology
Volume41
Issue number6
DOIs
Publication statusPublished - Dec 2009

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Partial Epilepsy
Age Distribution
Electroencephalography
Age Groups
Incidence

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Yoshinaga, H., Kobayashi, K., Ishizaki, Y., Wakai, M., Tominaga, Y., Matsuoka, T., & Ohtsuka, Y. (2009). Age-Dependent Spike Localization in Various Epileptic Syndromes. Pediatric Neurology, 41(6), 440-444. https://doi.org/10.1016/j.pediatrneurol.2009.06.005

Age-Dependent Spike Localization in Various Epileptic Syndromes. / Yoshinaga, Harumi; Kobayashi, Katsuhiro; Ishizaki, Yumiko; Wakai, Mari; Tominaga, Yusuke; Matsuoka, Takanori; Ohtsuka, Yoko.

In: Pediatric Neurology, Vol. 41, No. 6, 12.2009, p. 440-444.

Research output: Contribution to journalArticle

Yoshinaga, H, Kobayashi, K, Ishizaki, Y, Wakai, M, Tominaga, Y, Matsuoka, T & Ohtsuka, Y 2009, 'Age-Dependent Spike Localization in Various Epileptic Syndromes', Pediatric Neurology, vol. 41, no. 6, pp. 440-444. https://doi.org/10.1016/j.pediatrneurol.2009.06.005
Yoshinaga, Harumi ; Kobayashi, Katsuhiro ; Ishizaki, Yumiko ; Wakai, Mari ; Tominaga, Yusuke ; Matsuoka, Takanori ; Ohtsuka, Yoko. / Age-Dependent Spike Localization in Various Epileptic Syndromes. In: Pediatric Neurology. 2009 ; Vol. 41, No. 6. pp. 440-444.
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