Age- and division-of-labour-dependent differential expression of a novel non-coding RNA, Nb-1, in the brain of worker honeybees, Apis mellifera L.

H. Tadano, Y. Yamazaki, Hideaki Takeuchi, T. Kubo

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

To elucidate the molecular mechanisms underlying honeybee social behaviours, we identified a novel gene, Nb-1, whose expression in the worker brain changes according to the age-dependent division of labour in normal colonies. The open reading frames contained in the Nb-1 cDNA were not conserved in the homologue of a related species, suggesting that the Nb-1 gene product is a non-coding RNA. The distribution of Nb-1-expressing cells partially overlapped that of octopamine-immunoreactive cells and neurosecretory cells, the latter of which are involved in the synthesis and secretion of juvenile hormone (JH). Octopamine and JH control worker task transition, and thus Nb-1 might be involved in task transition through the modulation of octopamine/JH synthesis and secretion.

Original languageEnglish
Pages (from-to)715-726
Number of pages12
JournalInsect Molecular Biology
Volume18
Issue number6
DOIs
Publication statusPublished - Dec 2009
Externally publishedYes

Fingerprint

Octopamine
Juvenile Hormones
octopamine
worker honey bees
Untranslated RNA
Bees
juvenile hormones
Apis mellifera
brain
Brain
secretion
neurosecretory cells
synthesis
Social Behavior
social behavior
Open Reading Frames
Genes
honey bees
open reading frames
genes

Keywords

  • Apis mellifera
  • Division of labour
  • Neurosecretory cell
  • Non-coding RNA
  • Octopamine

ASJC Scopus subject areas

  • Insect Science
  • Molecular Biology
  • Genetics

Cite this

Age- and division-of-labour-dependent differential expression of a novel non-coding RNA, Nb-1, in the brain of worker honeybees, Apis mellifera L. / Tadano, H.; Yamazaki, Y.; Takeuchi, Hideaki; Kubo, T.

In: Insect Molecular Biology, Vol. 18, No. 6, 12.2009, p. 715-726.

Research output: Contribution to journalArticle

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