Advantages of TOF-SIMS analysis of hydroxyapatite and fluorapatite in comparison with XRD, HR-TEM and FT-IR

Masayuki Okazaki, Isao Hirata, Takuya Matsumoto, Junzo Takahashi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The chemical analysis of hydroxyapatite and fluorapatite was carried out using time-of-flight secondary ion mass spectrometry (TOF-SIMS). Hydroxyapatite and fluorapatite were synthesized at 80±1°C and pH 7.4±0.2. Fluorapatite was better crystallized, with its (300) reflection shifted to a slightly higher angle. High-resolution transmission electron microscopy clearly revealed a typical, regular hexagonal cross section perpendicular to the c-axis for fluorapatite and a flattened hexagonal cross section for hydroxyapatite. FT-IR spectra of fluorapatite confirmed the absence of OH absorption peak - which was seen in hydroxyapatite at about 3570 cm-1. TOF-SIMS mass spectra showed a peak at 40 amu due to calcium. In addition, a peak at 19 amu due to fluorine could be clearly seen, although the intensities of PO, PO 2, and PO3 were very low. It was confirmed that TOF-SIMS clearly showed the differences between positive and negative mass spectra of hydroxyapatite and fluorapatite, especially for F-. We concluded that TOF-SIMS exhibited distinct advantages compared with other methods of analysis.

Original languageEnglish
Pages (from-to)508-514
Number of pages7
JournalDental Materials Journal
Volume24
Issue number4
Publication statusPublished - Dec 2005
Externally publishedYes

Fingerprint

Secondary Ion Mass Spectrometry
Durapatite
Secondary ion mass spectrometry
Hydroxyapatite
Transmission electron microscopy
High resolution transmission electron microscopy
Fluorine
Calcium
Transmission Electron Microscopy
fluorapatite
Chemical analysis

Keywords

  • Fluorapatite
  • Hydroxyapatite
  • Tof-sims

ASJC Scopus subject areas

  • Dentistry(all)
  • Biomaterials

Cite this

Advantages of TOF-SIMS analysis of hydroxyapatite and fluorapatite in comparison with XRD, HR-TEM and FT-IR. / Okazaki, Masayuki; Hirata, Isao; Matsumoto, Takuya; Takahashi, Junzo.

In: Dental Materials Journal, Vol. 24, No. 4, 12.2005, p. 508-514.

Research output: Contribution to journalArticle

@article{727dd0e4d26e421ebc9e32322cb5d699,
title = "Advantages of TOF-SIMS analysis of hydroxyapatite and fluorapatite in comparison with XRD, HR-TEM and FT-IR",
abstract = "The chemical analysis of hydroxyapatite and fluorapatite was carried out using time-of-flight secondary ion mass spectrometry (TOF-SIMS). Hydroxyapatite and fluorapatite were synthesized at 80±1°C and pH 7.4±0.2. Fluorapatite was better crystallized, with its (300) reflection shifted to a slightly higher angle. High-resolution transmission electron microscopy clearly revealed a typical, regular hexagonal cross section perpendicular to the c-axis for fluorapatite and a flattened hexagonal cross section for hydroxyapatite. FT-IR spectra of fluorapatite confirmed the absence of OH absorption peak - which was seen in hydroxyapatite at about 3570 cm-1. TOF-SIMS mass spectra showed a peak at 40 amu due to calcium. In addition, a peak at 19 amu due to fluorine could be clearly seen, although the intensities of PO, PO 2, and PO3 were very low. It was confirmed that TOF-SIMS clearly showed the differences between positive and negative mass spectra of hydroxyapatite and fluorapatite, especially for F-. We concluded that TOF-SIMS exhibited distinct advantages compared with other methods of analysis.",
keywords = "Fluorapatite, Hydroxyapatite, Tof-sims",
author = "Masayuki Okazaki and Isao Hirata and Takuya Matsumoto and Junzo Takahashi",
year = "2005",
month = "12",
language = "English",
volume = "24",
pages = "508--514",
journal = "Dental Materials Journal",
issn = "0287-4547",
publisher = "Japanese Society for Dental Materials and Devices",
number = "4",

}

TY - JOUR

T1 - Advantages of TOF-SIMS analysis of hydroxyapatite and fluorapatite in comparison with XRD, HR-TEM and FT-IR

AU - Okazaki, Masayuki

AU - Hirata, Isao

AU - Matsumoto, Takuya

AU - Takahashi, Junzo

PY - 2005/12

Y1 - 2005/12

N2 - The chemical analysis of hydroxyapatite and fluorapatite was carried out using time-of-flight secondary ion mass spectrometry (TOF-SIMS). Hydroxyapatite and fluorapatite were synthesized at 80±1°C and pH 7.4±0.2. Fluorapatite was better crystallized, with its (300) reflection shifted to a slightly higher angle. High-resolution transmission electron microscopy clearly revealed a typical, regular hexagonal cross section perpendicular to the c-axis for fluorapatite and a flattened hexagonal cross section for hydroxyapatite. FT-IR spectra of fluorapatite confirmed the absence of OH absorption peak - which was seen in hydroxyapatite at about 3570 cm-1. TOF-SIMS mass spectra showed a peak at 40 amu due to calcium. In addition, a peak at 19 amu due to fluorine could be clearly seen, although the intensities of PO, PO 2, and PO3 were very low. It was confirmed that TOF-SIMS clearly showed the differences between positive and negative mass spectra of hydroxyapatite and fluorapatite, especially for F-. We concluded that TOF-SIMS exhibited distinct advantages compared with other methods of analysis.

AB - The chemical analysis of hydroxyapatite and fluorapatite was carried out using time-of-flight secondary ion mass spectrometry (TOF-SIMS). Hydroxyapatite and fluorapatite were synthesized at 80±1°C and pH 7.4±0.2. Fluorapatite was better crystallized, with its (300) reflection shifted to a slightly higher angle. High-resolution transmission electron microscopy clearly revealed a typical, regular hexagonal cross section perpendicular to the c-axis for fluorapatite and a flattened hexagonal cross section for hydroxyapatite. FT-IR spectra of fluorapatite confirmed the absence of OH absorption peak - which was seen in hydroxyapatite at about 3570 cm-1. TOF-SIMS mass spectra showed a peak at 40 amu due to calcium. In addition, a peak at 19 amu due to fluorine could be clearly seen, although the intensities of PO, PO 2, and PO3 were very low. It was confirmed that TOF-SIMS clearly showed the differences between positive and negative mass spectra of hydroxyapatite and fluorapatite, especially for F-. We concluded that TOF-SIMS exhibited distinct advantages compared with other methods of analysis.

KW - Fluorapatite

KW - Hydroxyapatite

KW - Tof-sims

UR - http://www.scopus.com/inward/record.url?scp=33644824098&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33644824098&partnerID=8YFLogxK

M3 - Article

VL - 24

SP - 508

EP - 514

JO - Dental Materials Journal

JF - Dental Materials Journal

SN - 0287-4547

IS - 4

ER -