Adult T‐Cell Leukemia/Lymphoma and Cutaneous T‐Cell Lymphoma Are They Related?

Mizuho Yamada, M. Takigawa, K. Iwatsuki, F. Inoue

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

ABSTRACT: Comparative studies were performed on clinical and laboratory features of four patients with different types of T‐cell lymphoma of the skin; adult T‐cell leukemia/lymphoma (ATLL), Sézary syndrome, mycosis fungoides, and Ki‐1‐positive lymphoma. All neoplastic cells studied showed a helper‐inducer T‐cell phenotype. A Ki‐1‐positive lymphoma is distinct from other types of cutaneous lymphomas because of unique morphologic and phenotypic features. Clonal proliferation of lymphocytes infected by human T‐cell lymphotrophic virus (HTLV)‐l distinguishes ATLL from other T‐cell lymphomas of the skin, especially in the endemic area of ATLL. From the pathogeneic point of view, ATLL should not be included in a group with mycosis fungoides and Sezary syndrome.

Original languageEnglish
Pages (from-to)107-113
Number of pages7
JournalInternational Journal of Dermatology
Volume28
Issue number2
DOIs
Publication statusPublished - Mar 1989

    Fingerprint

ASJC Scopus subject areas

  • Dermatology

Cite this