Adsorption and desorption behaviors of cetylpyridinium chloride on hydroxyapatite nanoparticles with different morphologies

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Abstract

Application of hydroxyapatite (HAp) nanoparticles to repair damaged enamel has attracted recent attention. In this study, HAp nanoparticles with various morphologies (spherical, short-rod, long-rod and fiber morphologies) were synthesized via chemical precipitation methods without the addition of template molecules, and the adsorption/desorption behaviors of a cationic antibacterial agent, cetylpyridinium chloride (CPC), on the HAp nanoparticles were evaluated. The adsorption of CPC on each HAp nanoparticle showed Langmuir-type adsorption, and the short-rod/long-rod HAp nanoparticles showed thermodynamically more stable adsorption of CPC than that with the spherical/fiber HAp nanoparticles. The desorption rate of CPC from the short-rod/long-rod HAp nanoparticles was slower than that of the spherical/fiber HAp nanoparticles. The HAp nanoparticles with different CPC release profiles presented here have potential applications as nanoparticulate enamel repair agents with antibacterial properties.

Original languageEnglish
Pages (from-to)651-658
Number of pages8
JournalDental Materials Journal
Volume35
Issue number4
DOIs
Publication statusPublished - 2016

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Keywords

  • Adsorption and desorption
  • Antibacterial
  • Cetylpyridinium chloride
  • Hydroxyapatite
  • Nanoparticle

ASJC Scopus subject areas

  • Dentistry(all)
  • Ceramics and Composites

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