Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium

Yong Li; Man Li Zhang; Bin Cong; Si Ming Wang; Mei Dong; Françoise Sauriol; Chang Hong Huo; Qing Wen Shi; Yu Cheng Gu; Hiromasa Kiyota

doi:10.1271/bbb.110234

Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium

Yong Li, Man Li Zhang, Bin Cong, Si Ming Wang, Mei Dong, Françoise Sauriol, Chang Hong Huo, Qing Wen Shi, Yu Cheng Gu, Hiromasa Kiyota

Research output: Contribution to journal › Article

17 Citations (Scopus)

Abstract

Achillinin A (2β,3β-epoxy-1α,4β,10α- trihydroxyguai- 11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LCkj and QG-90 cells with 50% inhibitory concentration (IC ₅₀) values of 5.8, 10 and 0.31μM, respectively.

Original language	English
Pages (from-to)	1554-1556
Number of pages	3
Journal	Bioscience, Biotechnology and Biochemistry
Volume	75
Issue number	8
DOIs	https://doi.org/10.1271/bbb.110234
Publication status	Published - Aug 29 2011
Externally published	Yes

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Keywords

Achillea millefolium
Flower
Guaianolide
Isolation

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

Cite this

Li, Y., Zhang, M. L., Cong, B., Wang, S. M., Dong, M., Sauriol, F., Huo, C. H., Shi, Q. W., Gu, Y. C., & Kiyota, H. (2011). Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. Bioscience, Biotechnology and Biochemistry, 75(8), 1554-1556. https://doi.org/10.1271/bbb.110234

Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. / Li, Yong; Zhang, Man Li; Cong, Bin; Wang, Si Ming; Dong, Mei; Sauriol, Françoise; Huo, Chang Hong; Shi, Qing Wen; Gu, Yu Cheng; Kiyota, Hiromasa.

In: Bioscience, Biotechnology and Biochemistry, Vol. 75, No. 8, 29.08.2011, p. 1554-1556.

Research output: Contribution to journal › Article

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10.1271/bbb.110234