Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium

Yong Li, Man Li Zhang, Bin Cong, Si Ming Wang, Mei Dong, Françoise Sauriol, Chang Hong Huo, Qing Wen Shi, Yu Cheng Gu, Hiromasa Kiyota

Research output: Contribution to journal › Article

17 Citations (Scopus)

Abstract

Achillinin A (2β,3β-epoxy-1α,4β,10α- trihydroxyguai- 11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LCkj and QG-90 cells with 50% inhibitory concentration (IC 50) values of 5.8, 10 and 0.31μM, respectively.

Original languageEnglish
Pages (from-to)1554-1556
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume75
Issue number8
DOIs
Publication statusPublished - 2011
Externally publishedYes

Keywords

  • Achillea millefolium
  • Flower
  • Guaianolide
  • Isolation

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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    • Cite this

    Li, Y., Zhang, M. L., Cong, B., Wang, S. M., Dong, M., Sauriol, F., Huo, C. H., Shi, Q. W., Gu, Y. C., & Kiyota, H. (2011). Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. Bioscience, Biotechnology and Biochemistry, 75(8), 1554-1556. https://doi.org/10.1271/bbb.110234