Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium

Yong Li, Man Li Zhang, Bin Cong, Si Ming Wang, Mei Dong, Françoise Sauriol, Chang Hong Huo, Qing Wen Shi, Yu Cheng Gu, Hiromasa Kiyota

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Achillinin A (2β,3β-epoxy-1α,4β,10α- trihydroxyguai- 11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LCkj and QG-90 cells with 50% inhibitory concentration (IC 50) values of 5.8, 10 and 0.31μM, respectively.

Original languageEnglish
Pages (from-to)1554-1556
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume75
Issue number8
DOIs
Publication statusPublished - 2011
Externally publishedYes

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Achillea
Inhibitory Concentration 50

Keywords

  • Achillea millefolium
  • Flower
  • Guaianolide
  • Isolation

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Analytical Chemistry
  • Organic Chemistry

Cite this

Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. / Li, Yong; Zhang, Man Li; Cong, Bin; Wang, Si Ming; Dong, Mei; Sauriol, Françoise; Huo, Chang Hong; Shi, Qing Wen; Gu, Yu Cheng; Kiyota, Hiromasa.

In: Bioscience, Biotechnology and Biochemistry, Vol. 75, No. 8, 2011, p. 1554-1556.

Research output: Contribution to journalArticle

Li, Y, Zhang, ML, Cong, B, Wang, SM, Dong, M, Sauriol, F, Huo, CH, Shi, QW, Gu, YC & Kiyota, H 2011, 'Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium', Bioscience, Biotechnology and Biochemistry, vol. 75, no. 8, pp. 1554-1556. https://doi.org/10.1271/bbb.110234
Li, Yong ; Zhang, Man Li ; Cong, Bin ; Wang, Si Ming ; Dong, Mei ; Sauriol, Françoise ; Huo, Chang Hong ; Shi, Qing Wen ; Gu, Yu Cheng ; Kiyota, Hiromasa. / Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. In: Bioscience, Biotechnology and Biochemistry. 2011 ; Vol. 75, No. 8. pp. 1554-1556.
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AU - Zhang, Man Li

AU - Cong, Bin

AU - Wang, Si Ming

AU - Dong, Mei

AU - Sauriol, Françoise

AU - Huo, Chang Hong

AU - Shi, Qing Wen

AU - Gu, Yu Cheng

AU - Kiyota, Hiromasa

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