Acceleration of apatite nucleation on parallel aligned Ti-substrates with optimum gaps by UV-light Pre-irradiation

Satoshi Hayakawa, Keita Uetsuki, Akinori Kochi, Yuki Shirosaki, Akiyoshi Osaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A recently developed "GRAPE® technology" provides titanium or titanium alloy implants with spontaneous apatite-forming ability in vitro, which requires properly designed gaps and optimum heat treatment in air. In this study, pure titanium pieces were thermally oxidized in air and pre-irradiated by UV-light under different environmental conditions such as in air or in ultra-pure water before aligning pairs of specimens in the GRAPE® set-up, i.e., two pieces of titanium substrates were aligned parallel to each other with optimum gap width (spatial design). Then, they were soaked in Kokubo's simulated body fluid (SBF, pH7.4, 36.5°C) for 1-2 days to clarify how the UV-light pre-irradiation affects the in vitro apatite nucleation on the substrates under the specific spatial design. UV-light pre-irradiation in water led to the deposition of a large number of apatite particles within 1 day, and showed apatite X-ray diffraction, although UV-light pre-irradiation in air and non-pretreated specimens gave the deposition of a few apatite particles and did not show any apatite X-ray diffraction. These results indicated that the rate of primary heterogeneous nucleation of apatite increased by UV-light pre-irradiation in ultra-pure water. TFXRD patterns of the surface of the substrates thermally oxidized in air at 500°C showed the peak at 2θ= 27° assignable to the 110 diffraction of rutile phase of titanium dioxide (ICDD-JCPDS data #21-1276). Previous studies reported that the primary heterogeneous nucleation must be induced by Ti-OH groups on titanium oxide layer. Probably, the UV-light pre-irradiation in ultra-pure water can increase the number of Ti-OH groups on the surface, resulting in accelerated primary heterogeneous nucleation of apatite.

Original languageEnglish
Title of host publicationBioceramics 23
Pages936-939
Number of pages4
DOIs
Publication statusPublished - Jan 1 2012
Event23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011 - Istanbul, Turkey
Duration: Nov 6 2011Nov 9 2011

Publication series

NameKey Engineering Materials
Volume493-494
ISSN (Print)1013-9826

Other

Other23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011
CountryTurkey
CityIstanbul
Period11/6/1111/9/11

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Keywords

  • Apatite
  • Nucleation
  • Thermal oxidation
  • Titania
  • Titanium
  • UV-light irradiation

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Hayakawa, S., Uetsuki, K., Kochi, A., Shirosaki, Y., & Osaka, A. (2012). Acceleration of apatite nucleation on parallel aligned Ti-substrates with optimum gaps by UV-light Pre-irradiation. In Bioceramics 23 (pp. 936-939). (Key Engineering Materials; Vol. 493-494). https://doi.org/10.4028/www.scientific.net/KEM.493-494.936