Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction

Hirokazu Arimoto; Ichiro Hayakawa; Makoto Kuramoto; Daisuke Uemura

doi:10.1016/S0040-4039(97)10714-6

Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction

Hirokazu Arimoto, Ichiro Hayakawa, Makoto Kuramoto, Daisuke Uemura

Research output: Contribution to journal › Article › peer-review

95 Citations (Scopus)

Abstract

The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.

Original language	English
Pages (from-to)	861-862
Number of pages	2
Journal	Tetrahedron Letters
Volume	39
Issue number	8
DOIs	https://doi.org/10.1016/S0040-4039(97)10714-6
Publication status	Published - Feb 19 1998
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0040-4039(97)10714-6

Cite this

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title = "Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction",

abstract = "The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.",

author = "Hirokazu Arimoto and Ichiro Hayakawa and Makoto Kuramoto and Daisuke Uemura",

note = "Funding Information: Acknowledgments. This research was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, and Culture, Japan.",

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AU - Arimoto, Hirokazu

AU - Hayakawa, Ichiro

AU - Kuramoto, Makoto

AU - Uemura, Daisuke

N1 - Funding Information: Acknowledgments. This research was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, and Culture, Japan.

PY - 1998/2/19

Y1 - 1998/2/19

N2 - The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.

AB - The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.

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U2 - 10.1016/S0040-4039(97)10714-6

DO - 10.1016/S0040-4039(97)10714-6

M3 - Article

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EP - 862

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 8

ER -

Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction

Abstract

ASJC Scopus subject areas

UN SDGs

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