Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction

Hirokazu Arimoto; Ichiro Hayakawa; Makoto Kuramoto; Daisuke Uemura

doi:10.1016/S0040-4039(97)10714-6

Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction

Hirokazu Arimoto, Ichiro Hayakawa, Makoto Kuramoto, Daisuke Uemura

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.

Original language	English
Pages (from-to)	861-862
Number of pages	2
Journal	Tetrahedron Letters
Volume	39
Issue number	8
DOIs	https://doi.org/10.1016/S0040-4039(97)10714-6
Publication status	Published - Feb 19 1998
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Absolute stereocmemistry of halichlorine; a potent inhibitor of VCAM-1 induction",

abstract = "The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.",

author = "Hirokazu Arimoto and Ichiro Hayakawa and Makoto Kuramoto and Daisuke Uemura",

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AU - Kuramoto, Makoto

AU - Uemura, Daisuke

PY - 1998/2/19

Y1 - 1998/2/19

N2 - The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product.

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U2 - 10.1016/S0040-4039(97)10714-6

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

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