Absolute stereochemistry of amphidinolide E

Takaaki Kubota, Masashi Tsuda, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

The absolute configurations at eight chiral centers in amphidinolide E (1), a cytotoxic 19-membered macrolide isolated from a marine dinoflagellate Amphidinium sp., were determined to be 2R, 7R, 8R, 13S, 16S, 17R, 18R, and 19R on the basis of detailed analysis of NMR data and by chemical means.

Original languageEnglish
Pages (from-to)1651-1656
Number of pages6
JournalJournal of Organic Chemistry
Volume67
Issue number5
DOIs
Publication statusPublished - Mar 8 2002
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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