Abrupt enlargement of adrenal incidentaloma: A case of isolated adrenal metastasis

Tomoko Miyoshi, Fumio Otsuka, Jiro Suzuki, Kenichi Inagaki, Yoshihiro Kano, Toshio Ogura, Katsuyuki Kiura, Takashi Saika, Hirofumi Makino

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


A 56-year-old Japanese man was referred for examination of right adrenal tumor (3 cm). He had no apparent preexisting cancer by radiological workup and accordingly, the patient was considered as a nonfunctioning adrenocortical adenoma and scheduled for periodic CT scans every 6 months. However, five months after the initial diagnosis the patient complained of severe right back pain with remarkable enlargement of both adrenals (∼20-fold volume). Although the origin of adrenal tumor was uncertain by pathological workup, positron emission tomography (PET) scan with 18F-2-fluoro-D-deoxyglucose (FDG) eventually revealed a hot spot on left upper lung, which was consistent with a lesion of thickened bulla wall observed by chest CT. The present case is a very rare example of abrupt enlargement of bilateral adrenals due to clinically isolated adrenal metastasis, suggesting the requirement of frequent observation with greatest care regarding morphologic changes of adrenal incidentalomas.

Original languageEnglish
Pages (from-to)785-788
Number of pages4
JournalEndocrine journal
Issue number6
Publication statusPublished - 2005


  • Adrenal incidentaloma
  • Adrenal metastasis
  • Lung cancer
  • Positron emission tomography

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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