Abnormal fluorine-18-fluorodeoxyglucose uptake in benign esophageal leiomyoma

Kentaroh Miyoshi, Minoru Naito, Tsuyoshi Ueno, Shinji Hato, Hideo Ino

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A benign esophageal leiomyoma with abnormally increased fluorine-18-fluorodeoxyglucose uptake on positron emission tomography (PET) was resected thoracoscopically. The tumor, of which the maximum standardized uptake value of the lesion was 4.7, was well defined and 38 mm in diameter. Neither mitotic activity nor degeneration was found histologically; and immunoreactivity for CD34, CD117, MIB-1, and glucose transporter-1 was negative immunohistochemically. A diagnosis of gastrointestinal stromal tumor was ruled out by an oncogenic kinase gene mutation study. This case cautions against PET-dependent evaluation for malignant potential of esophageal submucosal tumors.

Original languageEnglish
Pages (from-to)629-632
Number of pages4
JournalGeneral Thoracic and Cardiovascular Surgery
Volume57
Issue number11
DOIs
Publication statusPublished - Nov 2009

Keywords

  • Esophageal leiomyoma
  • Positron emission tomography

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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