Abnormal auditory neural networks in patients with right hemispheric infarction, chronic dizziness, and moyamoya disease: A magnetoencephalogram study

Akihiko Kandori, Hiroshi Oe, Kotaro Miyashita, Hiroshi Date, Naoaki Yamada, Hiroaki Naritomi, Yoshihide Chiba, Tsuyoshi Miyashita, Keiji Tsukada

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The purpose of this study was to determine whether the auditory cortex is sensitive to cortical insults and to determine the specificity of the insults in three clinical situations with different cortical involvement. Auditory-evoked magnetic fields of ten normal subjects, 8 patients with right hemispheric infarction, 11 with chronic dizziness, and 2 with moyamoya disease were measured. To analyze the abnormality of auditory neural networks, the magnitude ratio and the angle difference (Δθ) between response vectors, which were determined from maximum current arrows corresponding to the N100m peak for contralateral and ipsilateral stimuli were used. A normal range of the parameters was defined so that abnormal values could be determined. Of the three parameters, Δθ was the most sensitive: 4 patients with right hemispheric infarction, 4 with chronic dizziness, and 1 with moyamoya disease had abnormal Δθ. The electrical activity in the patients with such abnormal Δθs had a circular current pattern. These findings suggest that right infarction lesions sometime affect the left auditory neural network, dizziness is caused by abnormal neural networks between the vestibular cortical area and the auditory cortex or by an imbalance between left and right auditory-cortex activities, and moyamoya-disease patients have almost normal auditory-electrical activity.

Original languageEnglish
Pages (from-to)273-283
Number of pages11
JournalNeuroscience Research
Volume44
Issue number3
DOIs
Publication statusPublished - Nov 1 2002
Externally publishedYes

Keywords

  • Auditory-evoked magnetic field
  • Chronic dizziness
  • Hemispheric infarction
  • Magnetoencephalogram
  • Magnetoencephalography
  • Moyamoya disease

ASJC Scopus subject areas

  • Neuroscience(all)

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