AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters

Xian Zhong Su, Jing Chen, Tohru Mizushima, Teruo Kuroda, Tomofusa Tsuchiya

Research output: Contribution to journalArticle

117 Citations (Scopus)

Abstract

We cloned a gene, abeM, for a multidrug efflux pump from Acinetobacter baumannii using Escherichia coli as the host. Sequence analysis revealed that AbeM is a member of the MATE family of pumps. AbeM was found to be an H +-coupled multidrug efflux pump and a unique member of the MATE family.

Original languageEnglish
Pages (from-to)4362-4364
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number10
DOIs
Publication statusPublished - Oct 2005

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Acinetobacter baumannii
Sequence Analysis
Escherichia coli
Genes

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters. / Su, Xian Zhong; Chen, Jing; Mizushima, Tohru; Kuroda, Teruo; Tsuchiya, Tomofusa.

In: Antimicrobial Agents and Chemotherapy, Vol. 49, No. 10, 10.2005, p. 4362-4364.

Research output: Contribution to journalArticle

Su, Xian Zhong ; Chen, Jing ; Mizushima, Tohru ; Kuroda, Teruo ; Tsuchiya, Tomofusa. / AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters. In: Antimicrobial Agents and Chemotherapy. 2005 ; Vol. 49, No. 10. pp. 4362-4364.
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