A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine

Jin Wang, Kosuke Sato, Yuichi Yoshida, Kenji Sakai, Toshihiko Kiwa

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Terahertz waves have gained increasingly more attention because of their unique characteristics and great potential in a variety of fields. In this study, we introduced the recent progress of our versatile terahertz chemical microscope (TCM) in the detection of small biomolecules, ions, cancer cells, and antibody–antigen immunoassaying. We highlight the advantages of our TCM for chemical sensing and biosensing, such as label-free, high-sensitivity, rapid response, non-pretreatment, and minute amount sample consumption, compared with conventional methods. Furthermore, we demonstrated its new application in detection of allergic-related histamine at low concentration in buffer solutions.

Original languageEnglish
Article number26
JournalPhotonics
Volume9
Issue number1
DOIs
Publication statusPublished - Jan 2022

Keywords

  • Antibody–antigen
  • Biological substances
  • Cancer cells
  • Histamine
  • Label-free
  • Potential distribution
  • Terahertz chemical microscope

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

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