Abstract
Solution 17O-NMR application to biological macromolecules is extremely limited. We describe here 17O-NMR observation of the 17O2-oxidized cysteine side chain of human Cu,Zn-superoxide dismutase in solution using selective 17O2 oxidation. 17O-NMR with the aid of 17O-labeling has wide potential to probe the environment and dynamics of oxidizable functionalities in proteins.
Original language | English |
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Pages (from-to) | 1449-1451 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 49 |
Issue number | 14 |
DOIs | |
Publication status | Published - Jan 22 2013 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry