TY - JOUR
T1 - A simple test for salivary gland function measuring resting and stimulated submandibular and sublingual secretions
AU - Kanehira, Takashi
AU - Hongou, Hirohisa
AU - Asano, Kozo
AU - Morita, Manabu
AU - Maeshima, Etsuko
AU - Matsuda, Akemi
AU - Sakamoto, Wataru
PY - 2014/2
Y1 - 2014/2
N2 - Objective This study examined the application of a simple screening test for salivary gland function by measuring resting and stimulated submandibular and sublingual secretions. Study Design An assay system was designed to use filter paper incorporating the chromophore of melanoidin or stimuli such as capsaicin and citric acid. We investigated the relationship between resting and stimulated secretions and melanoidin migration at 2 minutes for healthy and dry mouth groups. Results The healthy group showed a significant increase in the migration of melanoidin in the paper after citric acid or capsaicin stimulation. In contrast, patients with Sjögren syndrome showed no significant migration in spite of the stimulation. However, some participants with Sjögren syndrome or dry mouth showed a significant increase in the migration of melanoidin after stimulation. Conclusions These results show that the newly developed method should be useful for evaluation of residual salivary gland function and screening for hyposalivation with dry mouth.
AB - Objective This study examined the application of a simple screening test for salivary gland function by measuring resting and stimulated submandibular and sublingual secretions. Study Design An assay system was designed to use filter paper incorporating the chromophore of melanoidin or stimuli such as capsaicin and citric acid. We investigated the relationship between resting and stimulated secretions and melanoidin migration at 2 minutes for healthy and dry mouth groups. Results The healthy group showed a significant increase in the migration of melanoidin in the paper after citric acid or capsaicin stimulation. In contrast, patients with Sjögren syndrome showed no significant migration in spite of the stimulation. However, some participants with Sjögren syndrome or dry mouth showed a significant increase in the migration of melanoidin after stimulation. Conclusions These results show that the newly developed method should be useful for evaluation of residual salivary gland function and screening for hyposalivation with dry mouth.
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U2 - 10.1016/j.oooo.2013.10.001
DO - 10.1016/j.oooo.2013.10.001
M3 - Article
C2 - 24439915
AN - SCOPUS:84892896506
VL - 117
SP - 197
EP - 203
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
SN - 2212-4403
IS - 2
ER -