A simple and practical method for the stereoselective synthesis of (Z)-1-iodo-1-alkenes from 1,1-diiodo-1-alkenes

Isao Kadota, Hirokazu Ueno, Akio Ohno, Yoshinori Yamamoto

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Treatment of the 1,1-diiodo-1-alkenes 8, prepared from the corresponding aldehydes with CI4/PPh3, with Zn-Cu/AcOH in THF-MeOH gave the (Z)-1-iodo-1-alkenes 9, selectively, in good yields.

Original languageEnglish
Pages (from-to)8645-8647
Number of pages3
JournalTetrahedron Letters
Volume44
Issue number48
DOIs
Publication statusPublished - Nov 24 2003
Externally publishedYes

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Keywords

  • Diiodoalkenes
  • Iodoalkenes
  • Stereoselective reduction
  • Zinc

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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