A screening test for capsaicin-stimulated salivary flow using filter paper

A study for diagnosis of hyposalivation with a complaint of dry mouth

Takashi Kanehira, Tomotaka Yamaguchi, Kozo Asano, Manabu Morita, Etsuko Maeshima, Akemi Matsuda, Yoshihiro Fujii, Wataru Sakamoto

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: The purpose of this study was to develop a simple screening technique for diagnosis of hyposalivation with dry mouth by estimation of capsaicin-stimulated salivary flow using filter paper. Study design: An assay system comprising 5 spots containing starch and potassium iodide on filter paper incorporating or without capsaicin and a coloring reagent was designed. We investigated whether the number of colored spots using the filter paper incorporating capsaicin could distinguish between healthy subjects and subjects with hyposalivation and dry mouth. Results: In the healthy group (>200 μL/min; n = 33), the capsaicin-stimulated salivary flow significantly increased as compared with the resting salivary flow, from 1.2 ± 1.4 to 2.9 ± 1.3 colored spots (P <.05). In contrast, the hyposalivation group with dry mouth (

Original languageEnglish
Pages (from-to)73-80
Number of pages8
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Volume112
Issue number1
DOIs
Publication statusPublished - Jul 2011

Fingerprint

Xerostomia
Capsaicin
Mouth
Potassium Iodide
Starch
Healthy Volunteers

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery
  • Dentistry(all)
  • Oral Surgery

Cite this

A screening test for capsaicin-stimulated salivary flow using filter paper : A study for diagnosis of hyposalivation with a complaint of dry mouth. / Kanehira, Takashi; Yamaguchi, Tomotaka; Asano, Kozo; Morita, Manabu; Maeshima, Etsuko; Matsuda, Akemi; Fujii, Yoshihiro; Sakamoto, Wataru.

In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, Vol. 112, No. 1, 07.2011, p. 73-80.

Research output: Contribution to journalArticle

Kanehira, Takashi ; Yamaguchi, Tomotaka ; Asano, Kozo ; Morita, Manabu ; Maeshima, Etsuko ; Matsuda, Akemi ; Fujii, Yoshihiro ; Sakamoto, Wataru. / A screening test for capsaicin-stimulated salivary flow using filter paper : A study for diagnosis of hyposalivation with a complaint of dry mouth. In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 2011 ; Vol. 112, No. 1. pp. 73-80.
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