A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients

K. J. Murphy, E. Houdart, K. T. Szopinski, O. Levrier, L. Guimaraens, D. Kühne, L. Solymosi, N. J. Bartholdy, Kenji Sugiu, D. A. Rüfenacht

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: The purpose of this study was to determine the safety and reliability of the mechanical detachment system of a new platinum coil, Detach-18, when used as a vascular occlusive device for neurovascular disease. METHODS: Forty-one patients (nine male and 32 female patients; age range, 26-75 years; mean age, 54.4 years) underwent treatment at seven centers. Twenty-two patients had dural arteriovenous fistulae of the transverse sinus treated by a transvenous route. Fourteen patients underwent internal carotid artery occlusion in the treatment of aneurysms, meningioma, facial tumor, or carotid injury. One patient underwent occlusion of the basilar artery and one patient underwent occlusion of the vertebral artery for treatment of aneurysms. In two patients, coils were used as part of the treatment of their arteriovenous malformations. In all cases, the Detach-18 coils were delivered through a microcatheter with two distal markers. Two types of coils, a 0.015-inch-diameter "regular" coil and a 0.014-inch-diameter "soft" coil, were used. RESULTS: A total of 569 coils were used, 541 of which were detached. The number of coils in ranged from four to 53 (average number of coils, 14). The coils passed easily through the microcatheter. The detachment maneuver occurred within 10 to 25 s with 20 turns of the introducing wire. No premature coil detachment occurred. Complete occlusion of the vessel lumen was achieved in 35 cases. In three cases, 80% to 90% occlusion was achieved. In two cases, 70% to 80% occlusion was achieved. There were no device-related complications. CONCLUSION: The detachment system was safe, reliable, consistent, and fast. This is a useful system for coil embolization in neurovascular applications.

Original languageEnglish
Pages (from-to)341-344
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume22
Issue number2
Publication statusPublished - 2001
Externally publishedYes

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Platinum
Aneurysm
Transverse Sinuses
Central Nervous System Vascular Malformations
Equipment and Supplies
Basilar Artery
Vertebral Artery
Arteriovenous Malformations
Internal Carotid Artery
Meningioma
Therapeutics
Blood Vessels
Safety
Wounds and Injuries
Neoplasms

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Murphy, K. J., Houdart, E., Szopinski, K. T., Levrier, O., Guimaraens, L., Kühne, D., ... Rüfenacht, D. A. (2001). A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients. American Journal of Neuroradiology, 22(2), 341-344.

A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients. / Murphy, K. J.; Houdart, E.; Szopinski, K. T.; Levrier, O.; Guimaraens, L.; Kühne, D.; Solymosi, L.; Bartholdy, N. J.; Sugiu, Kenji; Rüfenacht, D. A.

In: American Journal of Neuroradiology, Vol. 22, No. 2, 2001, p. 341-344.

Research output: Contribution to journalArticle

Murphy, KJ, Houdart, E, Szopinski, KT, Levrier, O, Guimaraens, L, Kühne, D, Solymosi, L, Bartholdy, NJ, Sugiu, K & Rüfenacht, DA 2001, 'A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients', American Journal of Neuroradiology, vol. 22, no. 2, pp. 341-344.
Murphy KJ, Houdart E, Szopinski KT, Levrier O, Guimaraens L, Kühne D et al. A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients. American Journal of Neuroradiology. 2001;22(2):341-344.
Murphy, K. J. ; Houdart, E. ; Szopinski, K. T. ; Levrier, O. ; Guimaraens, L. ; Kühne, D. ; Solymosi, L. ; Bartholdy, N. J. ; Sugiu, Kenji ; Rüfenacht, D. A. / A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients. In: American Journal of Neuroradiology. 2001 ; Vol. 22, No. 2. pp. 341-344.
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abstract = "BACKGROUND AND PURPOSE: The purpose of this study was to determine the safety and reliability of the mechanical detachment system of a new platinum coil, Detach-18, when used as a vascular occlusive device for neurovascular disease. METHODS: Forty-one patients (nine male and 32 female patients; age range, 26-75 years; mean age, 54.4 years) underwent treatment at seven centers. Twenty-two patients had dural arteriovenous fistulae of the transverse sinus treated by a transvenous route. Fourteen patients underwent internal carotid artery occlusion in the treatment of aneurysms, meningioma, facial tumor, or carotid injury. One patient underwent occlusion of the basilar artery and one patient underwent occlusion of the vertebral artery for treatment of aneurysms. In two patients, coils were used as part of the treatment of their arteriovenous malformations. In all cases, the Detach-18 coils were delivered through a microcatheter with two distal markers. Two types of coils, a 0.015-inch-diameter {"}regular{"} coil and a 0.014-inch-diameter {"}soft{"} coil, were used. RESULTS: A total of 569 coils were used, 541 of which were detached. The number of coils in ranged from four to 53 (average number of coils, 14). The coils passed easily through the microcatheter. The detachment maneuver occurred within 10 to 25 s with 20 turns of the introducing wire. No premature coil detachment occurred. Complete occlusion of the vessel lumen was achieved in 35 cases. In three cases, 80{\%} to 90{\%} occlusion was achieved. In two cases, 70{\%} to 80{\%} occlusion was achieved. There were no device-related complications. CONCLUSION: The detachment system was safe, reliable, consistent, and fast. This is a useful system for coil embolization in neurovascular applications.",
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AU - Houdart, E.

AU - Szopinski, K. T.

AU - Levrier, O.

AU - Guimaraens, L.

AU - Kühne, D.

AU - Solymosi, L.

AU - Bartholdy, N. J.

AU - Sugiu, Kenji

AU - Rüfenacht, D. A.

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N2 - BACKGROUND AND PURPOSE: The purpose of this study was to determine the safety and reliability of the mechanical detachment system of a new platinum coil, Detach-18, when used as a vascular occlusive device for neurovascular disease. METHODS: Forty-one patients (nine male and 32 female patients; age range, 26-75 years; mean age, 54.4 years) underwent treatment at seven centers. Twenty-two patients had dural arteriovenous fistulae of the transverse sinus treated by a transvenous route. Fourteen patients underwent internal carotid artery occlusion in the treatment of aneurysms, meningioma, facial tumor, or carotid injury. One patient underwent occlusion of the basilar artery and one patient underwent occlusion of the vertebral artery for treatment of aneurysms. In two patients, coils were used as part of the treatment of their arteriovenous malformations. In all cases, the Detach-18 coils were delivered through a microcatheter with two distal markers. Two types of coils, a 0.015-inch-diameter "regular" coil and a 0.014-inch-diameter "soft" coil, were used. RESULTS: A total of 569 coils were used, 541 of which were detached. The number of coils in ranged from four to 53 (average number of coils, 14). The coils passed easily through the microcatheter. The detachment maneuver occurred within 10 to 25 s with 20 turns of the introducing wire. No premature coil detachment occurred. Complete occlusion of the vessel lumen was achieved in 35 cases. In three cases, 80% to 90% occlusion was achieved. In two cases, 70% to 80% occlusion was achieved. There were no device-related complications. CONCLUSION: The detachment system was safe, reliable, consistent, and fast. This is a useful system for coil embolization in neurovascular applications.

AB - BACKGROUND AND PURPOSE: The purpose of this study was to determine the safety and reliability of the mechanical detachment system of a new platinum coil, Detach-18, when used as a vascular occlusive device for neurovascular disease. METHODS: Forty-one patients (nine male and 32 female patients; age range, 26-75 years; mean age, 54.4 years) underwent treatment at seven centers. Twenty-two patients had dural arteriovenous fistulae of the transverse sinus treated by a transvenous route. Fourteen patients underwent internal carotid artery occlusion in the treatment of aneurysms, meningioma, facial tumor, or carotid injury. One patient underwent occlusion of the basilar artery and one patient underwent occlusion of the vertebral artery for treatment of aneurysms. In two patients, coils were used as part of the treatment of their arteriovenous malformations. In all cases, the Detach-18 coils were delivered through a microcatheter with two distal markers. Two types of coils, a 0.015-inch-diameter "regular" coil and a 0.014-inch-diameter "soft" coil, were used. RESULTS: A total of 569 coils were used, 541 of which were detached. The number of coils in ranged from four to 53 (average number of coils, 14). The coils passed easily through the microcatheter. The detachment maneuver occurred within 10 to 25 s with 20 turns of the introducing wire. No premature coil detachment occurred. Complete occlusion of the vessel lumen was achieved in 35 cases. In three cases, 80% to 90% occlusion was achieved. In two cases, 70% to 80% occlusion was achieved. There were no device-related complications. CONCLUSION: The detachment system was safe, reliable, consistent, and fast. This is a useful system for coil embolization in neurovascular applications.

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