A pyridylsilyl group expands the scope of catalytic intermolecular Pauson-Khand reactions

Kenichiro Itami, Koichi Mitsudo, Jun Ichi Yoshida

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Now even unstrained alkenes can be used in catalytic intermolecular Pauson-Khand reactions [Eq. (a)]. This is made possible by the use of the directing group dimethyl(2-pyridyl)silyl, which can be easily removed at the end of the reaction. Furthermore, one observes completely regioselective incorporation of substituents at the 4- and 5-positions of the 2-cyclopentenone structure.

Original languageEnglish
Pages (from-to)3481-3484
Number of pages4
JournalAngewandte Chemie - International Edition
Volume41
Issue number18
DOIs
Publication statusPublished - Sep 16 2002
Externally publishedYes

Keywords

  • Alkenes
  • Alkynes
  • Cycloadditions
  • Homogeneous catalysis
  • Silanes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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