We have newly made a specific biomolecule microsensor measuring leakage current and impedance with minute liposome solution that interacts with biomolecules such as protein. The microsensor was fabricated with a Si surface-bulk-micromachining process. K4[Fe(CN)6] solution was entrapped inside of liposome of 1,2-dipalmitoyl-sn-glycero-3-phosphocholline (DPPC) and Carbonic Anhydrase from Bovine (CAB) was used as added protein for the interaction. A clear leakage in nA order was observed for the CAB, indicating the microsensor detects the CAB through the liposome-protein interaction. The detectivity increased by about 7 times and the volume of solution was decreased by about 10,000 from the previous result.
|Number of pages||4|
|Publication status||Published - Sep 1 2009|
|Event||Eurosensors 23rd Conference - Lausanne, Switzerland|
Duration: Sep 6 2009 → Sep 9 2009
- Leakage current
ASJC Scopus subject areas
- Chemical Engineering(all)