A possible occurrence of genome reassortment among bipartite rhabdoviruses

Hideki Kondo, Keisuke Hirota, Kazuyuki Maruyama, Andika Ida Bagus, Nobuhiro Suzuki

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Orchid fleck virus (OFV) represents a rhabdovirus with a unique bipartite genome. OFV genetic diversity at the whole genome level has not been described. Using the partial genome sequence of RNA1, we have determined that several OFV isolates derived from orchids in Japan belong to two genetically distant subgroups: subgroup I, the members of which are distributed worldwide but previously not known in Asia, and subgroup II, which is commonly distributed in Japan. However, complete genome sequence analysis of a novel Japanese subgroup I isolate revealed that although its RNA1 sequence differs considerably from those of subgroup II isolates, its RNA2 sequence is almost identical to them. Based on phylogenetic and recombination analyses, the genome reassortment events were predicted to occur between OFV subgroups including other unseen strains. Our data show that genome reassortment contributes to the genetic diversities of the bipartite rhabdoviruses and its occurrence may be geographically constrained.

Original languageEnglish
Pages (from-to)18-25
Number of pages8
JournalVirology
Volume508
DOIs
Publication statusPublished - Aug 1 2017

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Keywords

  • Bipartite genome
  • Dichorhavirus
  • Evolution
  • Genetic variation
  • Mite
  • Negative strand RNA virus
  • Orchid fleck virus
  • Reassortment
  • Rhabdovirus

ASJC Scopus subject areas

  • Virology

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