A planar-type leakage current and impedance microsensor for detection of interaction between electrolyte-entrapping liposome and protein

Y. Ohara, P. Lorchirachoonkul, K. Yamashita, M. Noda, O. A. Alberto, T. Shimanouchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have developed a new leakage current microsensor by using simpler planar processes than Si-surface-bulk micromachining processes used in the previous microwell structure. This sensor fabrication and structure can easily make a target solution volume smaller than μL with excellent immobilization of the droplet and intact biomolecules as sensing elements, as a result, reduce effectively the background noise current in the microsensor and improve reproducibility of the results. The leakage current due to the biochemical interaction was successfully evaluated. Cole-Cole plots from the impedance analysis also show quantitative difference between with and without the interaction, depending on the charge-transfer impedance.

Original languageEnglish
Title of host publicationIMFEDK 2012 - 2012 International Meeting for Future of Electron Devices, Kansai
Pages146-147
Number of pages2
DOIs
Publication statusPublished - Jul 30 2012
Externally publishedYes
Event10th International Meeting for Future of Electron Devices, Kansai, IMFEDK 2012 - Osaka, Japan
Duration: May 9 2012May 11 2012

Publication series

NameIMFEDK 2012 - 2012 International Meeting for Future of Electron Devices, Kansai

Other

Other10th International Meeting for Future of Electron Devices, Kansai, IMFEDK 2012
CountryJapan
CityOsaka
Period5/9/125/11/12

Keywords

  • electrochemical
  • impedance
  • leakage current
  • liposome
  • microsensor
  • protein

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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