A pigmented calcifying cystic odontogenic tumor associated with compound odontoma: A case report and review of literature

Phuu P. Han, Hitoshi Nagatsuka, Chong H. Siar, Hidetsugu Tsujigiwa, Mehmet Gunduz, Ryo Tamamura, Silvia S. Borkosky, Naoki Katase, Noriyuki Nagai

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Pigmented intraosseous odontogenic lesions are rare with only 47 reported cases in the English literature. Among them, pigmented calcifying cystic odontogenic tumor, formerly known as calcifying odontogenic cyst, is the most common lesion with 20 reported cases. Methods: A case of pigmented calcifying cystic odontogenic tumor associated with odontoma occurring at the mandibular canine-premolar region of a young Japanese boy is presented with radiographic, and histological findings. Special staining, electron microscopic study and immunohistochemical staining were also done to characterize the pigmentation. Results: The pigments in the lesion were confirmed to be melanin by Masson-Fontana staining and by transmission electron microscopy. The presence of dendritic melanocytes within the lesion was also demonstrated by S-100 immunostaining. Conclusion: The present case report of pigmented calcifying cystic odontogenic tumor associated with odontoma features a comprehensive study on melanin and melanocytes, including histochemical, immunohistochemical and transmission electron microscopic findings.

Original languageEnglish
Article number35
JournalHead and Face Medicine
Volume3
Issue number1
DOIs
Publication statusPublished - 2007

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'A pigmented calcifying cystic odontogenic tumor associated with compound odontoma: A case report and review of literature'. Together they form a unique fingerprint.

Cite this