TY - JOUR
T1 - A pigmented calcifying cystic odontogenic tumor associated with compound odontoma
T2 - A case report and review of literature
AU - Han, Phuu P.
AU - Nagatsuka, Hitoshi
AU - Siar, Chong H.
AU - Tsujigiwa, Hidetsugu
AU - Gunduz, Mehmet
AU - Tamamura, Ryo
AU - Borkosky, Silvia S.
AU - Katase, Naoki
AU - Nagai, Noriyuki
PY - 2007
Y1 - 2007
N2 - Background: Pigmented intraosseous odontogenic lesions are rare with only 47 reported cases in the English literature. Among them, pigmented calcifying cystic odontogenic tumor, formerly known as calcifying odontogenic cyst, is the most common lesion with 20 reported cases. Methods: A case of pigmented calcifying cystic odontogenic tumor associated with odontoma occurring at the mandibular canine-premolar region of a young Japanese boy is presented with radiographic, and histological findings. Special staining, electron microscopic study and immunohistochemical staining were also done to characterize the pigmentation. Results: The pigments in the lesion were confirmed to be melanin by Masson-Fontana staining and by transmission electron microscopy. The presence of dendritic melanocytes within the lesion was also demonstrated by S-100 immunostaining. Conclusion: The present case report of pigmented calcifying cystic odontogenic tumor associated with odontoma features a comprehensive study on melanin and melanocytes, including histochemical, immunohistochemical and transmission electron microscopic findings.
AB - Background: Pigmented intraosseous odontogenic lesions are rare with only 47 reported cases in the English literature. Among them, pigmented calcifying cystic odontogenic tumor, formerly known as calcifying odontogenic cyst, is the most common lesion with 20 reported cases. Methods: A case of pigmented calcifying cystic odontogenic tumor associated with odontoma occurring at the mandibular canine-premolar region of a young Japanese boy is presented with radiographic, and histological findings. Special staining, electron microscopic study and immunohistochemical staining were also done to characterize the pigmentation. Results: The pigments in the lesion were confirmed to be melanin by Masson-Fontana staining and by transmission electron microscopy. The presence of dendritic melanocytes within the lesion was also demonstrated by S-100 immunostaining. Conclusion: The present case report of pigmented calcifying cystic odontogenic tumor associated with odontoma features a comprehensive study on melanin and melanocytes, including histochemical, immunohistochemical and transmission electron microscopic findings.
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U2 - 10.1186/1746-160X-3-35
DO - 10.1186/1746-160X-3-35
M3 - Article
C2 - 17892598
AN - SCOPUS:36049017765
SN - 1746-160X
VL - 3
JO - Head and Face Medicine
JF - Head and Face Medicine
IS - 1
M1 - 35
ER -