A phase II clinical trial evaluating the preventive effectiveness of Lactobacillus vaginal suppositories in patients with recurrent cystitis

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Abstract

Urinary tract infections (UTIs) are the most common bacterial infections in women, and many patients experience frequent recurrence. The aim of this report is to introduce an on-going prospective phase II clinical trial performed to evaluate the preventive effectiveness of Lactobacillus vaginal suppositories for prevention of recurrent cystitis. Patients enrolled in this study are administered vaginal suppositories containing the GAI 98322 strain of Lactobacillus crispatus every 2 days or 3 times a week for one year. The primary endpoint is recurrence of cystitis and the secondary endpoints are adverse events. Recruitment began in December 2013 and target sample size is 20 participants.

Original languageEnglish
Pages (from-to)299-302
Number of pages4
JournalActa medica Okayama
Volume70
Issue number4
Publication statusPublished - 2016

Keywords

  • Lactobacilli
  • Lactobacillus crispatus
  • Probiotics
  • Urinary tract infection
  • Vaginal suppository

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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