Abstract
The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.
| Original language | English |
|---|---|
| Pages (from-to) | 1050-1054 |
| Number of pages | 5 |
| Journal | Internal Medicine |
| Volume | 40 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Jan 1 2001 |
Keywords
- Antineutrophil cytoplasmic antibody (ANCA)
- Cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA)
- Leukocytoclastic vasculitis
- Polyangiitis overlap syndrome
- Proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA)
- Pulmonary hemorrhage
ASJC Scopus subject areas
- Internal Medicine
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Cite this
Miyata, M., Kanno, K., Nishimaki, T., Sakuma, F., Iwatsuki, K., & Kasukawa, R. (2001). A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura. Internal Medicine, 40(10), 1050-1054. https://doi.org/10.2169/internalmedicine.40.1050