A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura

M. Miyata, K. Kanno, T. Nishimaki, F. Sakuma, K. Iwatsuki, R. Kasukawa

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Abstract

The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.

Original languageEnglish
Pages (from-to)1050-1054
Number of pages5
JournalInternal Medicine
Volume40
Issue number10
Publication statusPublished - 2001
Externally publishedYes

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Keywords

  • Antineutrophil cytoplasmic antibody (ANCA)
  • Cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA)
  • Leukocytoclastic vasculitis
  • Polyangiitis overlap syndrome
  • Proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA)
  • Pulmonary hemorrhage

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Miyata, M., Kanno, K., Nishimaki, T., Sakuma, F., Iwatsuki, K., & Kasukawa, R. (2001). A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura. Internal Medicine, 40(10), 1050-1054.