A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura

M. Miyata; K. Kanno; T. Nishimaki; F. Sakuma; K. Iwatsuki; R. Kasukawa

doi:10.2169/internalmedicine.40.1050

A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura

M. Miyata, K. Kanno, T. Nishimaki, F. Sakuma, K. Iwatsuki, R. Kasukawa

Graduate School of Medicine Dentistry and Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.

Original language	English
Pages (from-to)	1050-1054
Number of pages	5
Journal	Internal Medicine
Volume	40
Issue number	10
DOIs	https://doi.org/10.2169/internalmedicine.40.1050
Publication status	Published - 2001

Keywords

Antineutrophil cytoplasmic antibody (ANCA)
Cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA)
Leukocytoclastic vasculitis
Polyangiitis overlap syndrome
Proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA)
Pulmonary hemorrhage

ASJC Scopus subject areas

Internal Medicine

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title = "A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Sch{\"o}nlein purpura",

abstract = "The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Sch{\"o}nlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Sch{\"o}nlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.",

keywords = "Antineutrophil cytoplasmic antibody (ANCA), Cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA), Leukocytoclastic vasculitis, Polyangiitis overlap syndrome, Proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA), Pulmonary hemorrhage",

author = "M. Miyata and K. Kanno and T. Nishimaki and F. Sakuma and K. Iwatsuki and R. Kasukawa",

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T1 - A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura

AU - Miyata, M.

AU - Kanno, K.

AU - Nishimaki, T.

AU - Sakuma, F.

AU - Iwatsuki, K.

AU - Kasukawa, R.

PY - 2001

Y1 - 2001

N2 - The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.

AB - The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.

KW - Antineutrophil cytoplasmic antibody (ANCA)

KW - Cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA)

KW - Leukocytoclastic vasculitis

KW - Polyangiitis overlap syndrome

KW - Proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA)

KW - Pulmonary hemorrhage

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