Abstract
The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.
Original language | English |
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Pages (from-to) | 1050-1054 |
Number of pages | 5 |
Journal | Internal Medicine |
Volume | 40 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2001 |
Keywords
- Antineutrophil cytoplasmic antibody (ANCA)
- Cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA)
- Leukocytoclastic vasculitis
- Polyangiitis overlap syndrome
- Proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA)
- Pulmonary hemorrhage
ASJC Scopus subject areas
- Internal Medicine