A novel serpin-like protein, B-43, exists in both neurons and astrocytes: an immunohistochemical study in the parietal region of the bovine brain

Masahiro Nishibori; Aiji Ohtsuka; Masahiro Kawabata; Naoki Nakaya; Takuro Murakalni; Kiyorni Saeki

doi:10.1016/0304-3940(95)12095-L

A novel serpin-like protein, B-43, exists in both neurons and astrocytes: an immunohistochemical study in the parietal region of the bovine brain

Masahiro Nishibori, Aiji Ohtsuka, Masahiro Kawabata, Naoki Nakaya, Takuro Murakalni, Kiyorni Saeki

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Abstract

The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The processes of B-43-like immunoreactive astrocytes were observed to extend to the vascular wall, forming the endfeet-like structures. B-43 may play a cooperative role with glia-derived nexin/protease nexin-1 and antichymotrypsin in the brain.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	Neuroscience Letters
Volume	200
Issue number	2
DOIs	https://doi.org/10.1016/0304-3940(95)12095-L
Publication status	Published - Nov 17 1995

Keywords

Astrocytes
Bovine brain
Neurons
Proteinase
Serine proteinase inhibitor

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(95)12095-L

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title = "A novel serpin-like protein, B-43, exists in both neurons and astrocytes: an immunohistochemical study in the parietal region of the bovine brain",

abstract = "The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The processes of B-43-like immunoreactive astrocytes were observed to extend to the vascular wall, forming the endfeet-like structures. B-43 may play a cooperative role with glia-derived nexin/protease nexin-1 and antichymotrypsin in the brain.",

keywords = "Astrocytes, Bovine brain, Neurons, Proteinase, Serine proteinase inhibitor",

author = "Masahiro Nishibori and Aiji Ohtsuka and Masahiro Kawabata and Naoki Nakaya and Takuro Murakalni and Kiyorni Saeki",

note = "Funding Information: This work was partly supported by a grant from the Kobayashi Magobe Memorial Medical Foundation and by Grant-in Aid from the Japanese Ministry of Education, Science and Culture, Japan.",

year = "1995",

month = nov,

day = "17",

doi = "10.1016/0304-3940(95)12095-L",

language = "English",

volume = "200",

pages = "125--128",

journal = "Neuroscience Letters",

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publisher = "Elsevier Ireland Ltd",

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T1 - A novel serpin-like protein, B-43, exists in both neurons and astrocytes

T2 - an immunohistochemical study in the parietal region of the bovine brain

AU - Nishibori, Masahiro

AU - Ohtsuka, Aiji

AU - Kawabata, Masahiro

AU - Nakaya, Naoki

AU - Murakalni, Takuro

AU - Saeki, Kiyorni

N1 - Funding Information: This work was partly supported by a grant from the Kobayashi Magobe Memorial Medical Foundation and by Grant-in Aid from the Japanese Ministry of Education, Science and Culture, Japan.

PY - 1995/11/17

Y1 - 1995/11/17

N2 - The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The processes of B-43-like immunoreactive astrocytes were observed to extend to the vascular wall, forming the endfeet-like structures. B-43 may play a cooperative role with glia-derived nexin/protease nexin-1 and antichymotrypsin in the brain.

AB - The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The processes of B-43-like immunoreactive astrocytes were observed to extend to the vascular wall, forming the endfeet-like structures. B-43 may play a cooperative role with glia-derived nexin/protease nexin-1 and antichymotrypsin in the brain.

KW - Astrocytes

KW - Bovine brain

KW - Neurons

KW - Proteinase

KW - Serine proteinase inhibitor

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DO - 10.1016/0304-3940(95)12095-L

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AN - SCOPUS:0028787614

SN - 0304-3940

VL - 200

SP - 125

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JO - Neuroscience Letters

JF - Neuroscience Letters

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ER -

A novel serpin-like protein, B-43, exists in both neurons and astrocytes: an immunohistochemical study in the parietal region of the bovine brain

Abstract

Keywords

ASJC Scopus subject areas

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