A novel serpin-like protein, B-43, exists in both neurons and astrocytes: an immunohistochemical study in the parietal region of the bovine brain

Masahiro Nishibori, Aiji Ohtsuka, Masahiro Kawabata, Naoki Nakaya, Takuro Murakalni, Kiyorni Saeki

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The processes of B-43-like immunoreactive astrocytes were observed to extend to the vascular wall, forming the endfeet-like structures. B-43 may play a cooperative role with glia-derived nexin/protease nexin-1 and antichymotrypsin in the brain.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalNeuroscience Letters
Volume200
Issue number2
DOIs
Publication statusPublished - Nov 17 1995

Keywords

  • Astrocytes
  • Bovine brain
  • Neurons
  • Proteinase
  • Serine proteinase inhibitor

ASJC Scopus subject areas

  • Neuroscience(all)

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