TY - JOUR
T1 - A novel C-C bond forming reaction of aryl- and alkenylsilanols. A halogen-free mizoroki-heck type reaction
AU - Hirabayashi, Kazunori
AU - Nishihara, Yasushi
AU - Mori, Atsunori
AU - Hiyama, Tamejiro
N1 - Funding Information:
Acknowledgment. The authors are indebted to Yamada Science Foundation for financial support. This work was also supported by Grants-in-Aid for Scientific Research Nos. 07405042 and 09239102 from Ministry of Education, Science, Sports and Culture, Japan.
PY - 1998/10/22
Y1 - 1998/10/22
N2 - When dimethyl(phenyl)silanol is subjected to an electron-deficient olefin in the presence of a stoichiometric amount of Pd(OAc)2, substitution of the C-H bond of the olefin by a phenyl group on the silanol occurs in 52- 86% yields. The reactions of several aryl- and alkenylsilanols with several olefins are also found to proceed in the system of 10 mol% of Pa(OAc)2, Cu(OAc)2 (3 mol), LiOAc (2 mol) to give the corresponding products in up to 69% yield.
AB - When dimethyl(phenyl)silanol is subjected to an electron-deficient olefin in the presence of a stoichiometric amount of Pd(OAc)2, substitution of the C-H bond of the olefin by a phenyl group on the silanol occurs in 52- 86% yields. The reactions of several aryl- and alkenylsilanols with several olefins are also found to proceed in the system of 10 mol% of Pa(OAc)2, Cu(OAc)2 (3 mol), LiOAc (2 mol) to give the corresponding products in up to 69% yield.
UR - http://www.scopus.com/inward/record.url?scp=0032558619&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032558619&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(98)01750-X
DO - 10.1016/S0040-4039(98)01750-X
M3 - Article
AN - SCOPUS:0032558619
VL - 39
SP - 7893
EP - 7896
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 43
ER -