A novel C-C bond forming reaction of aryl- and alkenylsilanols. A halogen-free mizoroki-heck type reaction

Kazunori Hirabayashi, Yasushi Nishihara, Atsunori Mori, Tamejiro Hiyama

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

When dimethyl(phenyl)silanol is subjected to an electron-deficient olefin in the presence of a stoichiometric amount of Pd(OAc)2, substitution of the C-H bond of the olefin by a phenyl group on the silanol occurs in 52- 86% yields. The reactions of several aryl- and alkenylsilanols with several olefins are also found to proceed in the system of 10 mol% of Pa(OAc)2, Cu(OAc)2 (3 mol), LiOAc (2 mol) to give the corresponding products in up to 69% yield.

Original languageEnglish
Pages (from-to)7893-7896
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number43
DOIs
Publication statusPublished - Oct 22 1998
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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