A novel 3,8-seco-taxane metabolite from the seeds of the Chinese yew, Taxus mairei

Qing Wen Shi, Li Geng Li, Zuo Ping Li, Cong Mei Cao, Hiromasa Kiyota

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The structure of a novel 3,8-seco-bicyclic taxanoid metabolite, isolated from the methanol extract of seeds of the Chinese yew, Taxus mairei, was established as (11αH)-3,8-seco-taxa-3E,7E,12(18)-triene-2α,6α, 9β-triol (1) on the basis of spectral analysis including 1H NMR, 13C NMR, HMQC, HMBC, NOESY and HR-FABMS.

Original languageEnglish
Pages (from-to)6301-6303
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number37
DOIs
Publication statusPublished - Sep 12 2005
Externally publishedYes

Keywords

  • Bicyclic taxanes
  • Isolation
  • Taxanes
  • Taxus mairei

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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