A novel 3,8-seco-taxane metabolite from the seeds of the Chinese yew, Taxus mairei

Qing Wen Shi, Li Geng Li, Zuo Ping Li, Cong Mei Cao, Hiromasa Kiyota

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The structure of a novel 3,8-seco-bicyclic taxanoid metabolite, isolated from the methanol extract of seeds of the Chinese yew, Taxus mairei, was established as (11αH)-3,8-seco-taxa-3E,7E,12(18)-triene-2α,6α, 9β-triol (1) on the basis of spectral analysis including 1H NMR, 13C NMR, HMQC, HMBC, NOESY and HR-FABMS.

Original languageEnglish
Pages (from-to)6301-6303
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number37
DOIs
Publication statusPublished - Sep 12 2005
Externally publishedYes

Fingerprint

Taxus
Metabolites
Methanol
Seed
Seeds
Nuclear magnetic resonance
Spectrum analysis
taxane
Carbon-13 Magnetic Resonance Spectroscopy
vitamin B 12 factor III
Proton Magnetic Resonance Spectroscopy

Keywords

  • Bicyclic taxanes
  • Isolation
  • Taxanes
  • Taxus mairei

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

A novel 3,8-seco-taxane metabolite from the seeds of the Chinese yew, Taxus mairei. / Shi, Qing Wen; Li, Li Geng; Li, Zuo Ping; Cao, Cong Mei; Kiyota, Hiromasa.

In: Tetrahedron Letters, Vol. 46, No. 37, 12.09.2005, p. 6301-6303.

Research output: Contribution to journalArticle

Shi, Qing Wen ; Li, Li Geng ; Li, Zuo Ping ; Cao, Cong Mei ; Kiyota, Hiromasa. / A novel 3,8-seco-taxane metabolite from the seeds of the Chinese yew, Taxus mairei. In: Tetrahedron Letters. 2005 ; Vol. 46, No. 37. pp. 6301-6303.
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