@article{71ac9fb8edf844068621ccf0f85b5485,
title = "A new taxane composed of two N-formyl rotamers from Taxus canadensis",
abstract = "A taxane with an amino-side chain on C-5 was identified for the first time from rooted cuttings of the Canadian yew, Taxus canadensis. The structure was characterized as 7β,9α,10β,13α-tetraacetoxy-5α-[3′-(N-formyl-N-methylamino)-3′-phenylpropanoyl]oxytaxa-4(20),12-diene (1) on the basis of 1D-, 2D-NMR data, and HR-FABMS analyses. The spectra revealed that in CDCl3 solution 1 was composed of two rotamers (1a and 1b) in a ratio of approximately 2:1.",
author = "Zhang, {Man Li} and Mei Dong and Li, {Xiao Ning} and Li, {Li Geng} and Fan{\c c}oise Sauriol and Huo, {Chang Hong} and Shi, {Qing Wen} and Gu, {Yu Cheng} and Hiromasa Kiyota and Bin Cong",
note = "Funding Information: Support for this research was kindly provided by the Foundation for Researching New Drugs of People{\textquoteright}s Republic of China (No.: 2003AA2Z3527), the Scientific Research Foundation for the Returned Overseas Chinese Scholars from Hebei Province and State Education Ministry of PR China, Syngenta Ltd. (2005-Hebei Medical University-Syngenta-01), and the Grant-in-aid from Japan Society for the Promotion of Science (19580120). We are pleased to thank Professor Nobuo Suzuki (Department of Environmental Biochemistry, Chiba University, Japan) for providing all the cells and facilities for the biological evaluation. ",
year = "2008",
month = may,
day = "19",
doi = "10.1016/j.tetlet.2008.03.115",
language = "English",
volume = "49",
pages = "3405--3408",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "21",
}