A new target for therapy in squamous cell carcinoma of the lung

Kadoaki Ohashi, William Pao

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Investigators report the identification of novel somatic mutations in the DDR2 kinase gene in squamous cell carcinoma of the lung. Cellular, biochemical, and human data suggest that tumor cells harboring DDR2 mutations have increased sensitivity to existing tyrosine kinase inhibitors, providing rationale for clinical trials of agents that inhibit DDR2 kinase in the disease.

Original languageEnglish
Pages (from-to)23-24
Number of pages2
JournalCancer discovery
Volume1
Issue number1
DOIs
Publication statusPublished - Jun 1 2011
Externally publishedYes

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ASJC Scopus subject areas

  • Oncology

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