A new route to 3-acyl-2-aminobenzofurans: Palladium-catalysed cycloisomerisation of 2-(cyanomethyl)phenyl esters

Masahito Murai, Koji Miki, Kouichi Ohe

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Treatment of 2-(cyanomethyl)phenyl esters with a catalytic amount of Pd(OAc)2, PCy3, and Zn afforded 3-acyl-2-aminobenzofuran derivatives in good to excellent yields, which can be used as building blocks for the synthesis of benzofuran fused heterocycles.

Original languageEnglish
Pages (from-to)3466-3468
Number of pages3
JournalChemical Communications
Issue number23
DOIs
Publication statusPublished - 2009
Externally publishedYes

Fingerprint

Palladium
Esters
Derivatives
palladium(II) acetate
benzofuran

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

A new route to 3-acyl-2-aminobenzofurans : Palladium-catalysed cycloisomerisation of 2-(cyanomethyl)phenyl esters. / Murai, Masahito; Miki, Koji; Ohe, Kouichi.

In: Chemical Communications, No. 23, 2009, p. 3466-3468.

Research output: Contribution to journalArticle

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