A new dipeptide, O-phosphoserylethanolamine isolated from Agkistroden blomhoffi (mamushi)

Noriyoshi Masuoka, Jianying Zhang, Leila Partoo, Jun Ohta, Kenji Sasaki, Hideo Ebinuma, Hiroyuki Kodama

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A new dipeptide was isolated from several tissues of Agkistroden blomhoffi (mamushi: a venomous snake in Japan), using ion-exchange resins and thin-layer chromatography. It was identified as O-phosphoserylethanolamine by mass spectrometry and comparison with synthetic compounds using several methods. This compound was contained in several mamushi tissues including the liver, heart, brain, bile, and muscle. The concentrations of O-phosphoserylethanolamine in the liver, brain, muscle, skin, heart, and bile were 7.17 ± 3.11, 16.98 ± 4.25, 37.37 ± 7.88, 37.56 ± 8.97, 23.93 ± 6.11, and 22.21 ± 5.76 μmol/g, respectively.

Original languageEnglish
Pages (from-to)184-188
Number of pages5
JournalArchives of Biochemistry and Biophysics
Volume407
Issue number2
DOIs
Publication statusPublished - 2002

Keywords

  • Mamushi
  • O-phosphoserylethanolamine
  • Seryl-O-phosphoethanolamine

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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