TY - JOUR
T1 - A neural mechanism underlying mating preferences for familiar individuals in medaka fish
AU - Okuyama, Teruhiro
AU - Yokoi, Saori
AU - Abe, Hideki
AU - Isoe, Yasuko
AU - Suehiro, Yuji
AU - Imada, Haruka
AU - Tanaka, Minoru
AU - Kawasaki, Takashi
AU - Yuba, Shunsuke
AU - Taniguchi, Yoshihito
AU - Kamei, Yasuhiro
AU - Okubo, Kataaki
AU - Shimada, Atsuko
AU - Naruse, Kiyoshi
AU - Takeda, Hiroyuki
AU - Oka, Yoshitaka
AU - Kubo, Takeo
AU - Takeuchi, Hideaki
PY - 2014
Y1 - 2014
N2 - Social familiarity affects mating preference among various vertebrates. Here, we show that visual contact of a potential mating partner before mating (visual familiarization) enhances female preference for the familiarized male, but not for an unfamiliarized male, in medaka fish. Terminal-nerve gonadotropin-releasing hormone 3 (TN-GnRH3) neurons, an extrahypothalamic neuromodulatory system, function as a gate for activating mating preferences based on familiarity. Basal levels of TN-GnRH3 neuronal activity suppress female receptivity for any male (default mode). Visual familiarization facilitates TN-GnRH3 neuron activity (preference mode), which correlates with female preference for the familiarized male. GnRH3 peptides, which are synthesized specifically in TN-GnRH3 neurons, are required for the mode-switching via self-facilitation. Our study demonstrates the central neural mechanisms underlying the regulation of medaka female mating preference based on visual social familiarity.
AB - Social familiarity affects mating preference among various vertebrates. Here, we show that visual contact of a potential mating partner before mating (visual familiarization) enhances female preference for the familiarized male, but not for an unfamiliarized male, in medaka fish. Terminal-nerve gonadotropin-releasing hormone 3 (TN-GnRH3) neurons, an extrahypothalamic neuromodulatory system, function as a gate for activating mating preferences based on familiarity. Basal levels of TN-GnRH3 neuronal activity suppress female receptivity for any male (default mode). Visual familiarization facilitates TN-GnRH3 neuron activity (preference mode), which correlates with female preference for the familiarized male. GnRH3 peptides, which are synthesized specifically in TN-GnRH3 neurons, are required for the mode-switching via self-facilitation. Our study demonstrates the central neural mechanisms underlying the regulation of medaka female mating preference based on visual social familiarity.
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U2 - 10.1126/science.1244724
DO - 10.1126/science.1244724
M3 - Article
C2 - 24385628
AN - SCOPUS:84892698941
VL - 343
SP - 91
EP - 94
JO - Science
JF - Science
SN - 0036-8075
IS - 6166
ER -