The treatment of patients with congenital leukemia is difficult and often results in a poor prognosis. We present here the case of a female child with congenital acute myeloid leukemia (AML) with t(8; 16) (pll; pl3) who received chemotherapy and survived for more than 10 years without relapse. A novel MOZ CBP chimera was found in her diagnostic sample. Although adult AML patients with MOZ CBP have mainly been reported as having therapy-related AML and showed poor prognoses, the present case supports the idea that AML with MOZ CBP in the pediatric population might show better prognoses.
|Number of pages||5|
|Journal||Acta medica Okayama|
|Publication status||Published - 2016|
- Congenital leukemia
- t(8 ; 16)(pll ;pl3)
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)