A Long-term survivor after congenital acute myeloid leukemia with t(8 ; 16)(p11 ; p13)

Takae Hanada, Kiichiro Kanamitsu, Kosuke Chayama, Takako Miyamura, Yui Kanazawa, Michiko Muraoka, Kana Washio, Masahide Imada, Misao Kageyama, Akihito Takeuchi, Kei Tamai, Megumi Oda, Akira Shimada

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3 Citations (Scopus)

Abstract

The treatment of patients with congenital leukemia is difficult and often results in a poor prognosis. We present here the case of a female child with congenital acute myeloid leukemia (AML) with t(8; 16) (pll; pl3) who received chemotherapy and survived for more than 10 years without relapse. A novel MOZ CBP chimera was found in her diagnostic sample. Although adult AML patients with MOZ CBP have mainly been reported as having therapy-related AML and showed poor prognoses, the present case supports the idea that AML with MOZ CBP in the pediatric population might show better prognoses.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalActa Medica Okayama
Volume70
Issue number1
Publication statusPublished - 2016
Externally publishedYes

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Keywords

  • AML
  • Congenital leukemia
  • MOZ-CBP
  • t(8 ; 16)(pll ;pl3)

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Hanada, T., Kanamitsu, K., Chayama, K., Miyamura, T., Kanazawa, Y., Muraoka, M., Washio, K., Imada, M., Kageyama, M., Takeuchi, A., Tamai, K., Oda, M., & Shimada, A. (2016). A Long-term survivor after congenital acute myeloid leukemia with t(8 ; 16)(p11 ; p13). Acta Medica Okayama, 70(1), 31-35.