A long-term survival case of metachronous para-aortic lymph node metastasis from intrahepatic cholangiocarcinoma, staining in the early phase with chronic virus-related hepatitis

Daisuke Nobuoka, Toshio Nakagohrf, Koji Kitada, Yuichiro Kato, Naoto Gotohda, Takahiro Kinoshita, Shinichiro Takahashi, Masaru Konishi, Motohiro Kojima, Taira Kinoshita

Research output: Contribution to journalArticle

Abstract

Lymph node metastasis is one of the most serious prognostic factors in patients with intrahepatic cholangiocarcinoma. Furthermore, treatment of recurrent intrahepatic cholangiocarcinoma is difficult. We report a rare case of long-term survival in a patient who had metachronous para-aortic lymph node metastasis from intrahepatic cholangiocarcinoma. A 70-year-old man was followed up after endoscopic mu-cosal resection for esophageal cancer and referred to our section with space-occupying lesion of the liver. Computed tomography (CT) demonstrated a 3.0-cm-diameter tumor located in S6, which was hy-perattenuated in the early phase. Tumor cells were heptitis B antigen positive. He underwent partial hepatectomy under a preoperative diagnosis of hepatocellular carcinoma. The histopathological diagnosis was intrahepatic cholangiocarcinoma. At 16 months after the first operation, CT showed a swollen lymph node behind the inferior vena cava. After the second operation, we diagnosed metachronous para-aortic lymph node metastasis of intrahepatic cholangiocarcinoma. At 26 months after the first operation, a swollen lymph node around the celiac artery was found. He underwent a third operation at another institution. The histopathological findings were moderately differentiated adenocarcinoma, which was the same as the previously resected tumors. The patient is still alive without recurrence 3 years after the third resection and over 5 years after the first operation.

Original languageEnglish
Pages (from-to)1142-1150
Number of pages9
JournalJapanese Journal of Gastroenterological Surgery
Volume44
Issue number9
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Hepatitis Viruses
Cholangiocarcinoma
Lymph Nodes
Staining and Labeling
Neoplasm Metastasis
Survival
Tomography
Celiac Artery
S 6
Neoplasms
Inferior Vena Cava
Hepatectomy
Esophageal Neoplasms
Hepatocellular Carcinoma
Adenocarcinoma
Antigens
Recurrence
Liver

Keywords

  • Intrahepatic cholangiocarcinoma
  • Lymph node metastasis
  • Recurrence

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

A long-term survival case of metachronous para-aortic lymph node metastasis from intrahepatic cholangiocarcinoma, staining in the early phase with chronic virus-related hepatitis. / Nobuoka, Daisuke; Nakagohrf, Toshio; Kitada, Koji; Kato, Yuichiro; Gotohda, Naoto; Kinoshita, Takahiro; Takahashi, Shinichiro; Konishi, Masaru; Kojima, Motohiro; Kinoshita, Taira.

In: Japanese Journal of Gastroenterological Surgery, Vol. 44, No. 9, 2011, p. 1142-1150.

Research output: Contribution to journalArticle

Nobuoka, Daisuke ; Nakagohrf, Toshio ; Kitada, Koji ; Kato, Yuichiro ; Gotohda, Naoto ; Kinoshita, Takahiro ; Takahashi, Shinichiro ; Konishi, Masaru ; Kojima, Motohiro ; Kinoshita, Taira. / A long-term survival case of metachronous para-aortic lymph node metastasis from intrahepatic cholangiocarcinoma, staining in the early phase with chronic virus-related hepatitis. In: Japanese Journal of Gastroenterological Surgery. 2011 ; Vol. 44, No. 9. pp. 1142-1150.
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