A homosexual Japanese man with acute hepatitis due to hepatitis B virus genotype Ae, concurrent with amebic colitis

Yasuhiro Miyake, Yoshiaki Iwasaki, Shin Ishikawa, Masashi Tatsukawa, Toru Nawa, Jun Kato, Akinobu Takaki, Haruhiko Kobashi, Kohsaku Sakaguchi, Yasushi Shiratori

Research output: Contribution to journalArticle

Abstract

We report herein a case with acute hepatitis due to hepatitis B virus genotype Ae, concurrent with amebic colitis. A 39-year-old homosexual Japanese man was admitted to our hospital with jaundice. Laboratory tests showed an elevation of transaminase and positivity for hepatitis B surface antigen and IgM-type antibody to hepatitis B core antigen. The hepatitis B virus genotype was determined to be Ae. Furthermore, a mud-like stool with blood and mucous had sometimes been noted during the past 3 years, and amebic colitis was shown by colonofiberscopy during hospitalization. The patient was diagnosed with acute hepatitis B, concurrent with amebic colitis, and was successfully treated with lamivudine and metronidazole. In Japanese patients with acute hepatitis B virus genotype A infection, homosexual activity tends to be high. Furthermore, in Japanese homosexual men, amebiasis has been increasing. Thus, in Japanese patients with acute hepatitis B, a determination of genotype should be performed in order to investigate the route of transmission of hepatitis B virus, and a search for amebiasis should be performed in patients with acute hepatitis due to hepatitis B virus genotype A. Furthermore, education of homosexual men regarding hepatitis B virus, hepatitis B virus vaccination, and amebiasis is urgently required. Copyright

Original languageEnglish
Pages (from-to)35-39
Number of pages5
JournalActa medica Okayama
Volume61
Issue number1
Publication statusPublished - Feb 1 2007

Keywords

  • Amebic colitis
  • Genotype
  • Hepatitis B virus
  • Homosexual
  • Lamivudine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Miyake, Y., Iwasaki, Y., Ishikawa, S., Tatsukawa, M., Nawa, T., Kato, J., Takaki, A., Kobashi, H., Sakaguchi, K., & Shiratori, Y. (2007). A homosexual Japanese man with acute hepatitis due to hepatitis B virus genotype Ae, concurrent with amebic colitis. Acta medica Okayama, 61(1), 35-39.