A Hepatoportal osmoreceptive afferent projection from nucleus tractus solitarius to caudal ventrolateral medulla

Motoi Kobashi, Akira Adachi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This study was performed to examine projection of nucleus tractus solitarii (NTS) neurons to the caudal ventrolateral medulla (cVLM) in rats. One hundred and seven neurons that responded antidromically to electrical stimulation of the cVLM were recorded within the NTS. Electrical stimulation of the hepatic branch of the vagus nerve (hepatic vagus) elicited facilitation on 62 neurons (facilitatory neurons) and suppression on 6 neurons (suppressed neurons). Effect of portal infusion of hypertonic saline was examined on 44 facilitatory and 4 suppressed neurons. Twelve facilitatory and 2 suppressed neurons showed a decrease in the discharge rate. One suppressed neuron showed an increase in the discharge rate. It is concluded that hepatoportal osmoreceptive signals are conveyed from the NTS to the cVLM. The responses are mostly characterized by the decrease in the discharge rate by portal infusion of hypertonic saline.

Original languageEnglish
Pages (from-to)775-778
Number of pages4
JournalBrain Research Bulletin
Volume24
Issue number6
DOIs
Publication statusPublished - 1990

Fingerprint

Solitary Nucleus
Neurons
Electric Stimulation
Vagus Nerve
Liver

Keywords

  • Hepatic vagus
  • Hepatoportal osmoreceptor
  • Nucleus tractus solitarius
  • Ventrolateral medulla

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

A Hepatoportal osmoreceptive afferent projection from nucleus tractus solitarius to caudal ventrolateral medulla. / Kobashi, Motoi; Adachi, Akira.

In: Brain Research Bulletin, Vol. 24, No. 6, 1990, p. 775-778.

Research output: Contribution to journalArticle

@article{ff5641f6e8d44034b145ae75d25d6cd3,
title = "A Hepatoportal osmoreceptive afferent projection from nucleus tractus solitarius to caudal ventrolateral medulla",
abstract = "This study was performed to examine projection of nucleus tractus solitarii (NTS) neurons to the caudal ventrolateral medulla (cVLM) in rats. One hundred and seven neurons that responded antidromically to electrical stimulation of the cVLM were recorded within the NTS. Electrical stimulation of the hepatic branch of the vagus nerve (hepatic vagus) elicited facilitation on 62 neurons (facilitatory neurons) and suppression on 6 neurons (suppressed neurons). Effect of portal infusion of hypertonic saline was examined on 44 facilitatory and 4 suppressed neurons. Twelve facilitatory and 2 suppressed neurons showed a decrease in the discharge rate. One suppressed neuron showed an increase in the discharge rate. It is concluded that hepatoportal osmoreceptive signals are conveyed from the NTS to the cVLM. The responses are mostly characterized by the decrease in the discharge rate by portal infusion of hypertonic saline.",
keywords = "Hepatic vagus, Hepatoportal osmoreceptor, Nucleus tractus solitarius, Ventrolateral medulla",
author = "Motoi Kobashi and Akira Adachi",
year = "1990",
doi = "10.1016/0361-9230(90)90139-Q",
language = "English",
volume = "24",
pages = "775--778",
journal = "Brain Research Bulletin",
issn = "0361-9230",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - A Hepatoportal osmoreceptive afferent projection from nucleus tractus solitarius to caudal ventrolateral medulla

AU - Kobashi, Motoi

AU - Adachi, Akira

PY - 1990

Y1 - 1990

N2 - This study was performed to examine projection of nucleus tractus solitarii (NTS) neurons to the caudal ventrolateral medulla (cVLM) in rats. One hundred and seven neurons that responded antidromically to electrical stimulation of the cVLM were recorded within the NTS. Electrical stimulation of the hepatic branch of the vagus nerve (hepatic vagus) elicited facilitation on 62 neurons (facilitatory neurons) and suppression on 6 neurons (suppressed neurons). Effect of portal infusion of hypertonic saline was examined on 44 facilitatory and 4 suppressed neurons. Twelve facilitatory and 2 suppressed neurons showed a decrease in the discharge rate. One suppressed neuron showed an increase in the discharge rate. It is concluded that hepatoportal osmoreceptive signals are conveyed from the NTS to the cVLM. The responses are mostly characterized by the decrease in the discharge rate by portal infusion of hypertonic saline.

AB - This study was performed to examine projection of nucleus tractus solitarii (NTS) neurons to the caudal ventrolateral medulla (cVLM) in rats. One hundred and seven neurons that responded antidromically to electrical stimulation of the cVLM were recorded within the NTS. Electrical stimulation of the hepatic branch of the vagus nerve (hepatic vagus) elicited facilitation on 62 neurons (facilitatory neurons) and suppression on 6 neurons (suppressed neurons). Effect of portal infusion of hypertonic saline was examined on 44 facilitatory and 4 suppressed neurons. Twelve facilitatory and 2 suppressed neurons showed a decrease in the discharge rate. One suppressed neuron showed an increase in the discharge rate. It is concluded that hepatoportal osmoreceptive signals are conveyed from the NTS to the cVLM. The responses are mostly characterized by the decrease in the discharge rate by portal infusion of hypertonic saline.

KW - Hepatic vagus

KW - Hepatoportal osmoreceptor

KW - Nucleus tractus solitarius

KW - Ventrolateral medulla

UR - http://www.scopus.com/inward/record.url?scp=0025368410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025368410&partnerID=8YFLogxK

U2 - 10.1016/0361-9230(90)90139-Q

DO - 10.1016/0361-9230(90)90139-Q

M3 - Article

C2 - 2372696

AN - SCOPUS:0025368410

VL - 24

SP - 775

EP - 778

JO - Brain Research Bulletin

JF - Brain Research Bulletin

SN - 0361-9230

IS - 6

ER -