TY - JOUR
T1 - A facile synthesis of 5′-end solid-anchored, 3′-end free oligodeoxyribonucleotides via the (5′→3′)-elongated phosphoramidite strategy
AU - Sakakura, Akira
AU - Hayakawa, Yoshihiro
N1 - Funding Information:
This work was supported in part by Grants-in-Aid for Scientific Research (No. 11101001) from the Ministry of Education, Science, Sports and Culture, by a Grant from “Research for the Future” Program of the Japan Society for the Promotion of Science (JSPS-RFTF97I00301), and by contributions from the Asahi Glass Foundation and the Daiko Foundation.
PY - 2001
Y1 - 2001
N2 - It is demonstrated that not only N2- but also O 6-protection of the guanine base is necessary for obtaining the oligodeoxyribonucleotides in high yields and at a high purity in the solid-phase synthesis via the (5′ → 3′)-chain elongated phosphoramidite approach.
AB - It is demonstrated that not only N2- but also O 6-protection of the guanine base is necessary for obtaining the oligodeoxyribonucleotides in high yields and at a high purity in the solid-phase synthesis via the (5′ → 3′)-chain elongated phosphoramidite approach.
UR - http://www.scopus.com/inward/record.url?scp=0035011096&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035011096&partnerID=8YFLogxK
U2 - 10.1081/NCN-100002082
DO - 10.1081/NCN-100002082
M3 - Article
C2 - 11393398
AN - SCOPUS:0035011096
VL - 20
SP - 213
EP - 227
JO - Nucleosides, Nucleotides and Nucleic Acids
JF - Nucleosides, Nucleotides and Nucleic Acids
SN - 1525-7770
IS - 3
ER -