A facile access to 3-allyl- and 3-benzyl-3-cephems via reductive addition/cylization of allenecarboxylate with allyl and benzyl halides in an Al/Pb/Ni redox system

Hideo Tanaka; Shin Ichi Sumida; Kouichi Sorajo; Sigeru Torii

doi:10.1039/C39940001461

A facile access to 3-allyl- and 3-benzyl-3-cephems via reductive addition/cylization of allenecarboxylate with allyl and benzyl halides in an Al/Pb/Ni redox system

Hideo Tanaka, Shin Ichi Sumida, Kouichi Sorajo, Sigeru Torii

Faculty of Engineering

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

A sequential reductive addition/cyclization reaction of allenecarboyxlate, derived from penicillin G, with allyl and benzyl halides was successfully performed by the aid of aluminium metal ad catalytic amounts of PbBr₂ and [NiCl₂(bipy)] to afford 3-allyl- and 3-benzyl-3-cephems, respectively.

Original language	English
Pages (from-to)	1461-1462
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	12
DOIs	https://doi.org/10.1039/C39940001461
Publication status	Published - Dec 1 1994

ASJC Scopus subject areas

Molecular Medicine

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10.1039/C39940001461

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A facile access to 3-allyl- and 3-benzyl-3-cephems via reductive addition/cylization of allenecarboxylate with allyl and benzyl halides in an Al/Pb/Ni redox system. / Tanaka, Hideo; Sumida, Shin Ichi; Sorajo, Kouichi; Torii, Sigeru.

In: Journal of the Chemical Society, Chemical Communications, No. 12, 01.12.1994, p. 1461-1462.

Research output: Contribution to journal › Article › peer-review

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abstract = "A sequential reductive addition/cyclization reaction of allenecarboyxlate, derived from penicillin G, with allyl and benzyl halides was successfully performed by the aid of aluminium metal ad catalytic amounts of PbBr2 and [NiCl2(bipy)] to afford 3-allyl- and 3-benzyl-3-cephems, respectively.",

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AU - Sorajo, Kouichi

AU - Torii, Sigeru

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AB - A sequential reductive addition/cyclization reaction of allenecarboyxlate, derived from penicillin G, with allyl and benzyl halides was successfully performed by the aid of aluminium metal ad catalytic amounts of PbBr2 and [NiCl2(bipy)] to afford 3-allyl- and 3-benzyl-3-cephems, respectively.

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