Abstract
Thirty units that responded antidromically to electrical stimulation of the zona incerta (ZI) or the dorsal portion of hypothalamus were recorded in the nucleus tractus solitarii (NTS). These units were analyzed in relation to hepatoportal afferent inputs. Electrical stimulation of the hepatic branch of the vagus nerve facilitated six units (facilitatory units) and suppressed 10 units (suppressed units). Effect of the portal infusion of hypertonic saline was examined on six facilitatory and eight suppressed units. One facilitatory unit and one suppressed unit increased their discharge rates in response to portal infusion. Four facilitatory units and one suppressed unit decreased their discharge rates in response to the same stimulation. Increased or decreased discharge rates in response to portal infusion of hypertonic saline were observed in units that responded antidromically to electrical stimulation of the paraventricular hypothalamic nucleus, the lateral hypothalamic area, or the ZI. It is concluded that hepatoportal osmoreceptive signals are conveyed to the hypothalamus or the ZI directly from the NTS.
| Original language | English |
|---|---|
| Pages (from-to) | 487-492 |
| Number of pages | 6 |
| Journal | Brain Research Bulletin |
| Volume | 20 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1988 |
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Keywords
- Hepatic vagus
- Hepatoportal osmoreceptor
- Hypothalamus
- Nucleus tractus solitarius
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
A direct hepatic osmoreceptive afferent projection from nucleus tractus solitarius to dorsal hypothalamus. / Kobashi, Motoi; Adachi, Akira.
In: Brain Research Bulletin, Vol. 20, No. 4, 1988, p. 487-492.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A direct hepatic osmoreceptive afferent projection from nucleus tractus solitarius to dorsal hypothalamus
AU - Kobashi, Motoi
AU - Adachi, Akira
PY - 1988
Y1 - 1988
N2 - Thirty units that responded antidromically to electrical stimulation of the zona incerta (ZI) or the dorsal portion of hypothalamus were recorded in the nucleus tractus solitarii (NTS). These units were analyzed in relation to hepatoportal afferent inputs. Electrical stimulation of the hepatic branch of the vagus nerve facilitated six units (facilitatory units) and suppressed 10 units (suppressed units). Effect of the portal infusion of hypertonic saline was examined on six facilitatory and eight suppressed units. One facilitatory unit and one suppressed unit increased their discharge rates in response to portal infusion. Four facilitatory units and one suppressed unit decreased their discharge rates in response to the same stimulation. Increased or decreased discharge rates in response to portal infusion of hypertonic saline were observed in units that responded antidromically to electrical stimulation of the paraventricular hypothalamic nucleus, the lateral hypothalamic area, or the ZI. It is concluded that hepatoportal osmoreceptive signals are conveyed to the hypothalamus or the ZI directly from the NTS.
AB - Thirty units that responded antidromically to electrical stimulation of the zona incerta (ZI) or the dorsal portion of hypothalamus were recorded in the nucleus tractus solitarii (NTS). These units were analyzed in relation to hepatoportal afferent inputs. Electrical stimulation of the hepatic branch of the vagus nerve facilitated six units (facilitatory units) and suppressed 10 units (suppressed units). Effect of the portal infusion of hypertonic saline was examined on six facilitatory and eight suppressed units. One facilitatory unit and one suppressed unit increased their discharge rates in response to portal infusion. Four facilitatory units and one suppressed unit decreased their discharge rates in response to the same stimulation. Increased or decreased discharge rates in response to portal infusion of hypertonic saline were observed in units that responded antidromically to electrical stimulation of the paraventricular hypothalamic nucleus, the lateral hypothalamic area, or the ZI. It is concluded that hepatoportal osmoreceptive signals are conveyed to the hypothalamus or the ZI directly from the NTS.
KW - Hepatic vagus
KW - Hepatoportal osmoreceptor
KW - Hypothalamus
KW - Nucleus tractus solitarius
UR - http://www.scopus.com/inward/record.url?scp=0024158307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024158307&partnerID=8YFLogxK
U2 - 10.1016/0361-9230(88)90139-6
DO - 10.1016/0361-9230(88)90139-6
M3 - Article
C2 - 3395861
AN - SCOPUS:0024158307
VL - 20
SP - 487
EP - 492
JO - Brain Research Bulletin
JF - Brain Research Bulletin
SN - 0361-9230
IS - 4
ER -