A convergent approach to the formal total synthesis of hemibrevetoxin B

Isao Kadota, Takashi Abe, Yukako Ishitsuka, Abeda S. Touchy, Ryoko Nagata, Yoshinori Yamamoto

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A convergent synthesis of the key synthetic intermediate of hemibrevetoxin B was achieved via the intramolecular allylation of an α-chloroacetoxy ether and subsequent ring-closing metathesis.

Original languageEnglish
Pages (from-to)219-221
Number of pages3
JournalTetrahedron Letters
Volume48
Issue number2
DOIs
Publication statusPublished - Jan 8 2007

Keywords

  • Convergent synthesis
  • Hemibrevetoxin B
  • Polycyclic ethers

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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  • Cite this

    Kadota, I., Abe, T., Ishitsuka, Y., Touchy, A. S., Nagata, R., & Yamamoto, Y. (2007). A convergent approach to the formal total synthesis of hemibrevetoxin B. Tetrahedron Letters, 48(2), 219-221. https://doi.org/10.1016/j.tetlet.2006.11.058