A concise approach to (±)-tubifoline based on the palladium-catalyzed cross-coupling reaction of indolylborate

Minoru Ishikura, Norinobu Takahashi, Koji Yamada, Takumi Abe

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

The palladium-catalyzed tandem cyclization-cross-coupling protocol using 1H-indol-2-yltrialkylborate (indolylborate) proved to be a versatile approach to the generation of 2-(4-piperidylmethyl)indole, which was successfully used for the preparation of (±)-tubifoline.

Original languageEnglish
Pages (from-to)107-118
Number of pages12
JournalHeterocycles
Volume75
Issue number1
DOIs
Publication statusPublished - Jan 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'A concise approach to (±)-tubifoline based on the palladium-catalyzed cross-coupling reaction of indolylborate'. Together they form a unique fingerprint.

Cite this