A comparative view of insect circadian clock systems

Kenji Tomioka, Akira Matsumoto

Research output: Contribution to journalArticle

100 Citations (Scopus)

Abstract

Recent studies revealed that the neuronal network controlling overt rhythms shows striking similarity in various insect orders. The pigment-dispersing factor seems commonly involved in regulating locomotor activity. However, there are considerable variations in the molecular oscillatory mechanism, and input and output pathways among insects. In Drosophila, autoregulatory negative feedback loops that consist of clock genes, such as period and timeless are believed to create 24-h rhythmicity. Although similar clock genes have been found in some insects, the behavior of their product proteins shows considerable differences from that of Drosophila. In other insects, mammalian-type cryptochrome (cry2) seems to work as a transcriptional repressor in the feedback loop. For photic entrainment, Drosophila type cryptochrome (cry1) plays the major role in Drosophila while the compound eyes are the major photoreceptor in others. Further comparative study will be necessary to understand how this variety of clock mechanisms derived from an ancestral one.

Original languageEnglish
Pages (from-to)1397-1406
Number of pages10
JournalCellular and Molecular Life Sciences
Volume67
Issue number9
DOIs
Publication statusPublished - May 2010

Fingerprint

Circadian Clocks
Drosophila
Insects
Cryptochromes
Periodicity
Locomotion
Genes
Proteins

Keywords

  • Circadian rhythm
  • Clock genes
  • Entrainment
  • Insect
  • Molecular mechanism
  • Neural network

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Molecular Medicine
  • Pharmacology
  • Cellular and Molecular Neuroscience
  • Medicine(all)

Cite this

A comparative view of insect circadian clock systems. / Tomioka, Kenji; Matsumoto, Akira.

In: Cellular and Molecular Life Sciences, Vol. 67, No. 9, 05.2010, p. 1397-1406.

Research output: Contribution to journalArticle

Tomioka, Kenji ; Matsumoto, Akira. / A comparative view of insect circadian clock systems. In: Cellular and Molecular Life Sciences. 2010 ; Vol. 67, No. 9. pp. 1397-1406.
@article{94edb6e1fce8425c9168b90d7364d26b,
title = "A comparative view of insect circadian clock systems",
abstract = "Recent studies revealed that the neuronal network controlling overt rhythms shows striking similarity in various insect orders. The pigment-dispersing factor seems commonly involved in regulating locomotor activity. However, there are considerable variations in the molecular oscillatory mechanism, and input and output pathways among insects. In Drosophila, autoregulatory negative feedback loops that consist of clock genes, such as period and timeless are believed to create 24-h rhythmicity. Although similar clock genes have been found in some insects, the behavior of their product proteins shows considerable differences from that of Drosophila. In other insects, mammalian-type cryptochrome (cry2) seems to work as a transcriptional repressor in the feedback loop. For photic entrainment, Drosophila type cryptochrome (cry1) plays the major role in Drosophila while the compound eyes are the major photoreceptor in others. Further comparative study will be necessary to understand how this variety of clock mechanisms derived from an ancestral one.",
keywords = "Circadian rhythm, Clock genes, Entrainment, Insect, Molecular mechanism, Neural network",
author = "Kenji Tomioka and Akira Matsumoto",
year = "2010",
month = "5",
doi = "10.1007/s00018-009-0232-y",
language = "English",
volume = "67",
pages = "1397--1406",
journal = "Cellular and Molecular Life Sciences",
issn = "1420-682X",
publisher = "Birkhauser Verlag Basel",
number = "9",

}

TY - JOUR

T1 - A comparative view of insect circadian clock systems

AU - Tomioka, Kenji

AU - Matsumoto, Akira

PY - 2010/5

Y1 - 2010/5

N2 - Recent studies revealed that the neuronal network controlling overt rhythms shows striking similarity in various insect orders. The pigment-dispersing factor seems commonly involved in regulating locomotor activity. However, there are considerable variations in the molecular oscillatory mechanism, and input and output pathways among insects. In Drosophila, autoregulatory negative feedback loops that consist of clock genes, such as period and timeless are believed to create 24-h rhythmicity. Although similar clock genes have been found in some insects, the behavior of their product proteins shows considerable differences from that of Drosophila. In other insects, mammalian-type cryptochrome (cry2) seems to work as a transcriptional repressor in the feedback loop. For photic entrainment, Drosophila type cryptochrome (cry1) plays the major role in Drosophila while the compound eyes are the major photoreceptor in others. Further comparative study will be necessary to understand how this variety of clock mechanisms derived from an ancestral one.

AB - Recent studies revealed that the neuronal network controlling overt rhythms shows striking similarity in various insect orders. The pigment-dispersing factor seems commonly involved in regulating locomotor activity. However, there are considerable variations in the molecular oscillatory mechanism, and input and output pathways among insects. In Drosophila, autoregulatory negative feedback loops that consist of clock genes, such as period and timeless are believed to create 24-h rhythmicity. Although similar clock genes have been found in some insects, the behavior of their product proteins shows considerable differences from that of Drosophila. In other insects, mammalian-type cryptochrome (cry2) seems to work as a transcriptional repressor in the feedback loop. For photic entrainment, Drosophila type cryptochrome (cry1) plays the major role in Drosophila while the compound eyes are the major photoreceptor in others. Further comparative study will be necessary to understand how this variety of clock mechanisms derived from an ancestral one.

KW - Circadian rhythm

KW - Clock genes

KW - Entrainment

KW - Insect

KW - Molecular mechanism

KW - Neural network

UR - http://www.scopus.com/inward/record.url?scp=77952316518&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952316518&partnerID=8YFLogxK

U2 - 10.1007/s00018-009-0232-y

DO - 10.1007/s00018-009-0232-y

M3 - Article

C2 - 20035363

AN - SCOPUS:77952316518

VL - 67

SP - 1397

EP - 1406

JO - Cellular and Molecular Life Sciences

JF - Cellular and Molecular Life Sciences

SN - 1420-682X

IS - 9

ER -