A combined light and scanning electron microscopy on human urinary cytology

Hiromi Kumon1, Yasutomo Nasu, Yosuke Matsumura, Hiroyuki Ohmori, Toshio Tanaka

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Approximately 250 bladder-washing and voided urine specimens from normal, and inflammatory and malignant lesions were examined using light microscopy (LM), scanning electron microscopy (SEM) and a newly-designed mesh. This specific mesh, containing 42 compartments in 25 mm2 on gelatine- coated glass-slip, permitted us the direct correlation of LM and SEM images. With SEM, malignancy of exfoliated urothelial cells mainly depended on the presence or absence of pleomorphic microvilli. Subsequently, a new “SEM grading” regarding human urinary cytology was proposed.

Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalMicroscopy
Volume32
Issue number1
DOIs
Publication statusPublished - Jan 1 1983

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Keywords

  • Human bladder cancer
  • Pleomorphic microvilli
  • Scanning electron microscopy (SEM)
  • Urinary cytology

ASJC Scopus subject areas

  • Structural Biology
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

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