Abstract
Approximately 250 bladder-washing and voided urine specimens from normal, and inflammatory and malignant lesions were examined using light microscopy (LM), scanning electron microscopy (SEM) and a newly-designed mesh. This specific mesh, containing 42 compartments in 25 mm2 on gelatine- coated glass-slip, permitted us the direct correlation of LM and SEM images. With SEM, malignancy of exfoliated urothelial cells mainly depended on the presence or absence of pleomorphic microvilli. Subsequently, a new “SEM grading” regarding human urinary cytology was proposed.
Original language | English |
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Pages (from-to) | 27-32 |
Number of pages | 6 |
Journal | Microscopy |
Volume | 32 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 1 1983 |
Keywords
- Human bladder cancer
- Pleomorphic microvilli
- Scanning electron microscopy (SEM)
- Urinary cytology
ASJC Scopus subject areas
- Structural Biology
- Instrumentation
- Radiology Nuclear Medicine and imaging